TCM Pathogenesis of IBS Treated with Modified Sanren Decoction Based on Triple Energizer Differentiation
Journal: Journal of Clinical Medicine Research DOI: 10.32629/jcmr.v7i2.5289
Abstract
Irritable Bowel Syndrome (IBS) is a prevalent functional gastrointestinal disorder with elusive pathogenesis and recurrent abdominal pain plus abnormal defecation. Western medicine merely offers symptomatic relief with poor long-term efficacy, while traditional Chinese medicine delivers stable curative effects via holistic syndrome differentiation. This paper explores IBS pathogenesis and therapeutic approaches under triple energizer differentiation, centering on Professor Huang Yahui's Modified Sanren Decoction. The triple energizer system jointly governs qi transformation and fluid metabolism: upper jiao lung dysfunction causes dampness pouring down; middle jiao spleen transportation disorder forms internal damp-heat (the core lesion); lower jiao liver-kidney disharmony triggers qi stagnation. The modified formula targets three jiaos separately: bitter apricot seed disperses lung qi to clear upper damp turbidity, amomum and largehead atractylodes tonify spleen and resolve middle damp-heat, coix seed drains lower dampness. Flexible modifications combined with Tongxie Yaofang address liver-spleen imbalance. Triple energizer differentiation breaks single zang-fu treatment limits, clarifies interlocked pathological mechanisms of multiple viscera, and provides an integrated TCM strategy for recurrent IBS.
Keywords
Sanjiao syndrome differentiation; Irritable Bowel Syndrome; Modified Sanren Decoction
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[2] XIONG LS, CHEN MH, CHEN HX, et al. A population based epidemiologic study of irritable bowel syndrome in South China: stratified randomized study by cluster sampling [J]. Aliment Pharmacol Ther, 2004, 19(11): 1217-1224.
[3] CELERI S, ACIK Y, DEVECIS E, et al. Epidemiological features of irritable bowel syndrome in a Turkish urban society[J]. J Gastroenterol Hepatol, 2004, 19(7): 738.
[4] Wang Yajie, Cong Yu, Yang Yang, et al. Discussion on Pathogenesis and Therapeutic Principles of Diarrhea-Predominant Irritable Bowel Syndrome Based on the Theory of Regulating Pivot and Unblocking Stomach[J]. Global Journal of Traditional Chinese Medicine, 2020, 13(09): 1634-1636.
[5] Chen Xiao, Tang Li, Liu Zhiqun, et al. Discussion on TCM Pathogenesis and Treatment of Diarrhea-Predominant Irritable Bowel Syndrome (Spleen Deficiency with Damp-Heat Syndrome in Middle Jiao) Based on Sanjiao Syndrome Differentiation[J]. Journal of Practical Traditional Chinese Internal Medicine, 2023, 37(11): 136-139. DOI:10.13729/j.issn.1671-7813.Z20221904
[6] Zhang Xiaoxia. Analysis on Zang-Fu Organ Functions[D]. Shandong University of Traditional Chinese Medicine, 2007.
[7] Yang Zeyu, Meng Zhizhou, Jia Yuanning, et al. Li Jianhong's Experience in Treating Wind-Constrained Blood-Heat Type Acne Based on the Theory of Stagnated Heat and Ministerial Fire[J]. Jilin Journal of Traditional Chinese Medicine, 2025, 45(05): 545-548. DOI:10.13463/j.cnki.jlzyy.2025.05.012.
[8] Guo Wenjuan, Hu Ke. Modified Zisheng Pill Combined with Mesalazine for 35 Cases of Diarrhea-Predominant Irritable Bowel Syndrome[J]. Jiangxi Journal of Traditional Chinese Medicine, 2013, 44(03): 33-34.
[9] Yang Min. Discussion on TCM Experience in Treating Constipation Induced by Chemotherapy after Breast Cancer Operation[J]. Guangming Journal of Chinese Medicine, 2019, 34(02): 306-308.
[10] Liu Siming, Wang Chuijie, Li Yufeng. Analysis of Professor Wang Chuijie's Clinical Experience in Treating Diarrhea-Predominant Irritable Bowel Syndrome[J]. Asia-Pacific Traditional Medicine, 2024, 20(03): 136-139.
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