Clinical Efficacy and Cardiac Function Analysis of Zhigancao Decoction Combined With Metoprolol in the Treatment of Coronary Heart Disease Arrhythmias

Journal: Journal of Clinical Medicine Research DOI: 10.32629/jcmr.v5i2.2328

Ting Wang

Cardiovascular Department of Baoji Third Hospital, Baoji 721000, Shaanxi, China

Abstract

Objective: To explore the clinical effect and cardiac function of moxibustion licorice decoction combined with metoprolol in the treatment of coronary heart disease arrhythmia. Method: 92 patients with coronary heart disease and arrhythmia admitted from January 2022 to December 2023 were selected as the analysis subjects. Divide into a control group and an observation group using envelope randomization method. The former is treated with metoprolol, while the latter is treated with moxibustion licorice soup and metoprolol. Compare clinical efficacy, cardiac function, heart rate variability, and adverse reactions. The total effective rate of the observation group treatment was 95.65%, which was higher than that of the control group 82.61% (X2=4.039, P=0.044); The LVESD and CO levels in the observation group were lower than those in the control group, while the LVEF and LVEDD levels were higher than those in the control group (P<0.05); The number of atrial premature beats and ventricular premature beats at 24 hours in the observation group was lower than that in the control group, and the levels of SDNN and SDANN were higher than those in the control group (P<0.05); The incidence of adverse reactions in the observation group was 6.52%, which was lower than that in the control group (X2=4.389, P=0.036). Conclusion: For patients with coronary heart disease and arrhythmia, moxibustion with licorice decoction combined with metoprolol has a clear effect, can improve heart function, reduce myocardial contractility, and is relatively safe.

Keywords

coronary heart disease and arrhythmia; moxibustion licorice soup; metoprolol; clinical effects; cardiac function

References

[1] Huang Weiqing, Du Tingting, Cai Yang. The therapeutic effect of Yiqi Yangxin formula on ventricular arrhythmia in coronary heart disease and its impact on hemorheological indicators and CXCL9 levels of myocardial ischemia [J]. Laboratory Medicine and Clinical, 2024,21 (08): 1046-1048+1053.
[2] Xie Yuhua, Chen Huiyang. The effect of metoprolol combined with amiodarone treatment on electrocardiogram, cardiac function, and symptom improvement in elderly patients with coronary heart disease complicated with arrhythmia [J]. Zhongwai Medical Journal, 2023,42 (12): 126-130.
[3] Qin Shiwei. Clinical value of modified Zhigancao decoction combined with Wenxin granules in the treatment of coronary heart disease with arrhythmia [J]. Practical Clinical Application of Integrated Traditional Chinese and Western Medicine, 2023,23 (01): 96-98+117.
[4] Interventional Cardiology Group of Cardiology Branch of Chinese Medical Association, Atherosclerosis and Coronary Heart Disease Group of Cardiology Branch of Chinese Medical Association, Professional Committee of Thrombosis Prevention and Treatment of Cardiovascular Physicians Branch of Chinese Medical Association, etc. Guidelines for Diagnosis and Treatment of Stable Coronary Heart Disease [J]. Chinese Journal of Cardiology, 2018,46 (9): 680-694.
[5] Zeng Xiaodong, Pan Lifeng. The therapeutic effect and cardiac function of metoprolol combined with amiodarone in patients with coronary heart disease and arrhythmia [J]. Shenzhen Journal of Integrated Traditional Chinese and Western Medicine, 2022, 32 (23): 69-71.
[6] Guo Zhihua, Li Yanru. The effect of Zhi Gan Cao Tang combined with metoprolol and amiodarone in the treatment of coronary heart disease with qi deficiency and blood stasis type combined with ventricular arrhythmia and its impact on vascular endothelial function and QT interval dispersion [J]. Clinical Medical Research and Practice, 2023,8 (01): 118-120.
[7] Song Banglin, Wu Fang. Observation on the efficacy and safety of modified Zhigancao Tang combined with conventional Western medicine in the treatment of coronary heart disease complicated with arrhythmia [J]. Guizhou Medical Journal, 2022, 46 (08): 1288-1289.
[8] Pan Zhimei. The therapeutic effect of Zhi Gan Cao Tang combined with metoprolol on patients with coronary heart disease and ventricular arrhythmias [J]. Journal of Shanxi Health Vocational College, 2022, 32 (04): 19-21.
[9] Han Xue. The therapeutic effect of metoprolol on patients with coronary heart disease complicated with arrhythmia and its impact on plasma APN levels [J]. Chinese Medical Guidelines, 2022-20 (07): 18-21.
[10] Liang Cuimei. Clinical effect of modified combination of metoprolol and roasted licorice decoction in the treatment of coronary heart disease arrhythmia with Qi and Yin deficiency type [J]. Inner Mongolia Traditional Chinese Medicine, 2021,40 (08): 25-26.

Copyright © 2024 Ting Wang

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License