Analysis of Risk Factors Associated with Parkinson's Disease in Li Region in Hainan Area of China

Journal: Journal of Clinical Medicine Research DOI: 10.32629/jcmr.v3i2.855

Shuge Wang1, Xinyao Sun1, Cui Chen2, Chenyu Yang3, Wujian Xie4, Na Lu5

1. The Second Clinical College of Hainan Medical University, Haikou 571199, Hainan, China
2. International School of Public Health and One Health of Hainan Medical University, Haikou 571199, Hainan, China
3. The First Clinical College of Hainan Medical University, Haikou 571199, Hainan, China
4. The First Affiliated Hospital of Hainan Medical University, Hainan, China
5. Clinical Skills Exprimental Teaching Ceter of Hainan Medical University, Haikou 571199, Hainan, China

Abstract

Objective — To analyse the risk factors associated with Parkinson's patients of Li ethnic groups in Hainan area. Methods — A retrospective survey study was conducted to select 81 cases of Parkinson's disease patients of Li ethnicity (Parkinson's group) and 110 cases of healthy population of Li ethnicity (control group), respectively, to collect data and conduct statistical analysis. Results — (1) GLU, UA, TG, HDL, LDL, Cys-C, Scr, BUN, ApoA, ApoB in the Li Parkinson's disease group were not statistically significant (P>0.05) compared with the control group. TC, Hcy and ApoB were significantly higher in the Li Parkinson's disease group than in the control group, and the differences were statistically significant (P<0.05). (2) Through Binary logistic regression analysis, the results showed that hypertension, TC and Hcy may be risk factors for the development of PD in the Li population. Conclusion — A history of hypertension and elevated cholesterol and homocysteine levels are independent risk factors for Parkinson's disease in Li patients in Hainan area.

Keywords

Parkinson's disease, risk factors, blood glucose, cholesterol, apolipoprotein a, apolipoprotein b, creatinine

Funding

Undergraduate Innovation and Entrepreneurship Training Program of Hainan Medical University research grants X202111810077. Project name: Correlation analysis of risk factors for Parkinson's syndrome in Li-Han ethnic groups in Hainan

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Copyright © 2022 Shuge Wang, Xinyao Sun, Cui Chen, Chenyu Yang, Wujian Xie, Na Lu

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