Journal of Clinical Medicine Research

Objective — To observe and compare the analgesic effects of different types of local anesthetics (Ropivacaine, Lidocaine) on the pain of patients in different periods after laparoscopic surgery. Methods — A total of 141 patients admitted to the Seventh Affiliated Hospital of Southern Medical University for laparoscopic surgery from Jan. 2021 to Aug. 2021 were randomly divided into 3 groups: Ropivacaine (group A), Lidocaine (group B) and Control (group C). In group A, Ropivacaine (0.5%, 10ml) was injected layer by layer around the incision after abdominal closure suture. Group B were injected with Lidocaine (1%, 10ml) around the incision. Group C applied with the same volume of normal saline around the incision instead of anesthetic. Visual analogue scale (VAS) scoring was performed 2h, 6h, 12h, 24h, 48h after surgery respectively. Patients' sore up to 5 were injected with Ambutritol, Ibuprofen and Flurbiprofen. The number of patients, frequency and dose were recorded. Meanwhile, the incidence of postoperative adverse reactions such as dizziness, headache, nausea and vomiting in 3 groups were recorded. Results — VAS scores of group A were significantly lower than those of group B and group C in all postoperative follow-up observation periods (2h, 6h, 12h, 24h, 48h), and the difference was statistically significant (P<0.05); VAS scores of group B was lower than that of group C at 2h and the difference was statistically significant (P<0.05), but there was no statistical significance in VAS scores at 6, 12, 24 and 48h after surgery compared with group C (P>0.05). The number of patients, frequency and dose of reuse of painkillers in group A (0) were lower than those in group B (3) and group C (11) within 48 hours after operation, and no adverse reactions such as dizziness, headache, nausea and vomiting occurred in group A, 11 in group B and 3 in group C. Conclusion — The application of Ropivacaine infiltration anesthesia in laparoscopic surgery after abdominal closure and suture can effectively reduce postoperative pain in patients, with obvious analgesic effect in early stage and long duration, which can improve the postoperative experience of patients, reduce postoperative adverse reactions. Thus, we should promote the application of such treatment protocol in clinical surgery.