Effect of Huaier Granule and Transcatheter Arterial Chemoembolization on the Treatment of Advanced Liver Cancer
Journal: Journal of Clinical Medicine Research DOI: 10.32629/jcmr.v2i3.458
Abstract
Objective — To explore the effect of Huaier granule combined with transcatheter arterial chemoembolization (TACE) in the treatment of advanced liver cancer. Methods — From January 2017 to January 2020, 150 patients with advanced liver cancer admitted to our hospital were selected as clinical subjects for a prospective non-randomized controlled study based on different treatment schedules. Among them, 50 patients were distributed to TACE group with TACE treatment alone. Besides, 50 patients were assigned to chemotherapy group and received systemic chemotherapy with Folfox4 regimen alone. Among them, 50 patients were distributed as the observation group. The therapeutic effects of the three groups were compared. Results: The effective rate and disease control rate in observation group were significantly higher than those in TACE group and chemotherapy group (P < 0.05). The rate of adr in observation group and TACE group was significantly lower than that in chemotherapy group (P < 0.05). The survival rate of observation group was significantly higher than that of TACE group and chemotherapy group after 12 months follow-up (P < 0.05). Conclusion — The combined treatment of huaier granule and TACE can improve the therapeutic effect and survival rate of patients with advanced liver cancer.
Keywords
advanced liver cancer, Huaier granule; transcatheter arterial chemoembolization (TACE)
Funding
2017 Zhejiang TCM Science and Technology Planning Project "Clinical study of Huaier granule combined with TACE in the treatment of lung metastasis of liver cancer" (2017ZA032)
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[2] Liu Jianfei, Li Feng, Wang Ningfang, et al. Effects of transcatheter arterial chemoembolization combined with radio frequency ablation on survival, liver function and T lymphocyte subgroup in patients with advanced hepatocellular carcinoma[J]. Progress in Modern Biomedicine, 2021, 21(9):1669-1672, 1701.
[3] Jin Dan, Liu Li, Wu Mingyong, et al. Effects of transcatheter arterial chemoembolization and thermoperfusion chemoembolization on liver function in patients with advanced hepatocellular carcinoma[J]. Modern Instruments, 2019, 25(3):56-60.
[4] Zhao Junyan, Lu Yan, Liu Xiaoya. Application of oxaliplatin combined with fluorouracil and pirubicin in the treatment of advanced hepatocellular carcinoma by transcatheter arterial chemoembolization and nursing intervention[J]. Chinese Journal of Rational Drug Use, 2021, 18(4):80-84.
[5] Li Xinyi, Wang Qimei, Deng Xiangsheng, et al. Clinical study of hepatic arterial infusion of Brucea javanica oil emulsion injection combined with lipiodol embolization in the treatment of advanced hepatocellular carcinoma[J]. Hunan Journal of Traditional Chinese Medicine, 2020, 36(8):5-7, 17.
[6] He Chaoxiong, Feng Huigang, Weng Yu. Clinical study of TACE combined with radioactive 125I seed and Huaier granule in the treatment of advanced hepatocellular carcinoma[J]. Chinese Medical Innovations, 2018, 15(6):13-16.
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