白囊耙齿菌的代谢特性、生物活性及多领域应用研究综述
Journal: Ecological Environment and Protection DOI: 10.32629/eep.v9i1.3017
Abstract
白囊耙齿菌兼具药用价值与工业应用潜力,其代谢产物与酶系统多样且功能优异。本文综述其次生代谢产物、提取物活性及酶学应用研究进展：代谢产物涵盖倍半萜类、三萜类等,具细胞毒性、抗炎、抗菌等活性；提取物富含多糖、蛋白质等,具有肾脏保护、抗疲劳等功效,且肾脏保护作用已实现临床转化；其漆酶、锰过氧化物酶等在生物质转化、环境修复等领域前景广阔。文末分析研究不足并展望未来,为该菌深度开发提供参考。
Keywords
白囊耙齿菌；次生代谢产物；生物活性；生物转化；环境治理
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[2] 刘亚亚,张秀丽,秦一统,等.子午岭林区野生白囊耙齿菌分离与ITS分子鉴定[J].现代农业科技,2022,(16):43-46.
[3] Dong X, Song X, Dong C. Nutritional requirements for mycelial growth of milk-white toothed mushroom, Irpex lacte us (Agaricomycetes), in submerged culture[J]. International Journal of Medicinal Mushrooms,2017,19(9).
[4] 董晓明,宋新华,刘宽博,等.药用真菌白囊耙齿菌的研究现状及展望[J].菌物学报,2017,36(01):28-34.
[5] Ding J H,Li Z H, Feng T, et al. Tremulane sesquiterpenes from cultures of the basidiomycete Irpex lacteus[J]. Fitotera pia,2018,125:245-248.
[6] Tang Y, Zhao Z Z, Feng T, et al. Triterpenes with unusual modifications from the fruiting bodies of the medicinal fungus Irpex lacteus[J].Phytochemistry,2019,162:21-28.
[7] Tang Y,Zhao Z Z,Yao J N,et al.Irpeksins A-E,1,10-seco -eburicane-type triterpenoids from the medicinal fungus Irpex lacteus and their anti-NO activity[J].Journal of Natural Products,2018,81(10):2163-2168.
[8] Sadahiro Y,Kato H,Williams R M,et al.Irpexine, an isoin dolinone alkaloid produced by coculture of endophytic fungi, Irpex lacteus and Phaeosphaeria oryzae[J]. Journal of Natural Products,2020,83(5):1368-1373.
[9] 杨真威,姜瑞芝,陈英红,等.耙齿菌糖蛋白的提取分离、理化性质及抗炎活性[J].天然产物研究与开发,2005,(03):280-282.
[10] 石陶圣,吴凌,赵兴红,等.响应面法优化白囊耙齿菌多糖提取条件[J].中国医药工业杂志,2009,40(10):743-746.
[11] Wu L,Zhang X G,Shi T S,et al.Optimization of extract ion for Irpex lacteus polysaccharides and its bioactivity[J]. Lishizhen Medicine and Materia Medica Research, 2010, 21(12):3094-3096.
[12] Ji G,Yao Z,Zhao Y,et al.Systems Pharmacology and Multi -Omics Elucidation of Irpex lacteus Polysaccharides in the Treatment of Lupus Nephritis Through PI3K/AKT/NF-κB Pathw ay Inhibition[J].Pharmaceuticals,2025,18(11):1619.
[13] 潘静怡,杨悦,王方.核桃粕酶解多肽的抗氧化与抗疲劳活性研究[J].食品安全质量检测学报,2026,17(01):305-315.
[14] Wang J,Li C,Hu W, et al.Studies on the anti-fatigue activities of Irpex lacteus polysaccharide-enriched extract in mouse model[J].Pakistan Journal of Pharmaceutical Sciences,2019,32(3).
[15] Yuan J,Li Z,Yu Y,et al.Natural compounds in the manage ment of polycystic ovary syndrome: a comprehensive review of hormonal regulation and therapeutic potential[J]. Frontiers in Nutrition,2025,12:1520695.
[16] Zhou Y Y,Wu Y Q,Chong C J,et al.Irpex lacteus polysacch aride exhibits therapeutic potential for ovarian fibrosis in PCOS rats via the TGF-β1/smad pathway[J].Heliyon,2023,9(8).
[17] Mirabella,N.;Castellani, V.; Sala,S. Current options for the valorization of food manufacturing waste:A review.J. Clean.Prod.2014,65,28-41.
[18] Anwar,Z.;Gulfraz,M.;Irshad,M.Agro-industrial lignoce llulosic biomass a key to unlock the futurebio-energy: A brief review.J.Radiat.Res.Appl.Sc.2014,7,163-173.
[19] Cherubin, M.R.; Oliveira, D.M.D.S.; Feigl, B.J.; Pimentel, L.G.; Lisboa, I.P.; Gmach, M.R.; Varanda, L.L.;Morais, M.C.; Satiro, L.S.;Popin,G.V.;et al.Crop residue harvest for bioenergy production and itsimplications on soil functioning and plant growth: A review.Sci.Agricola 2018,75,255-272.
[20] Prasad,S.,Singh,A.,Joshi,H.C.,2007.Ethanol as an altern ative fuel fromagricultural, industrial and urban residues. Resources Conservation andRecycling 50,1-39.
[21] Song L,Liu B, Zhu Q, et al. Genomic and Transcriptomic Insights into Carbon-Source and Temporal Induction of a Diverse Set of Lignocellulolytic Enzymes in Irpex lacteus QJ[J].Journal of Fungi,2025,11(12):882.
[22] Xu C,Ma F, Zhang X, et al. Biological pretreatment of corn stover by Irpex lacteus for enzymatic hydrolysis[J].Journal of agricultural and food chemistry,2010,58(20):10893-10898.
[23] García-Torreiro M, López-Abelairas M, Lu-Chau T A, et al.Fungal pretreatment of agricultural residues for bioet hanol production[J]. Industrial Crops and Products, 2016, 89:486-492.2017,36,28-34.
[24] Baborová P, Möder M, Baldrian P, et al. Purification of a new manganese peroxidase of the white-rot fungus Irpex lacteus, and degradation of polycyclic aromatic hydrocarbons by the enzyme[J].Research in Microbiology,2006,157(3):248-253.
[25] Moon D S, Song H G. Degradation of alkylphenols by white rot fungus Irpex lacteus and its manganese peroxidase [J].Applied biochemistry and biotechnology,2012,168(3):542-549.
[26] Li J,Li X,Da Y,et al.Sustainable environmental remedia tion via biomimetic multifunctional lignocellulosic nano-fra mework[J].Nature communications,2022,13(1):4368.
[27] Choi Y S, Long Y, Kim M J, et al. Decolorization and degradation of synthetic dyes by Irpex lacteus KUC8958[J]. Journal of Environmental Science and Health, Part A, 2013,48(5):501-508.
[28] Qin X, Zhang J, Zhang X, et al. Induction, purification and characterization of a novel manganese peroxidase from Irpex lacteus CD2 and its application in the decolorization of different types of dye[J].PLoS One,2014,9(11):e113282.
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