噪声暴露与心血管系统疾病的相关性研究
Journal: Basic Medical Theory Research DOI: 10.32629/bmtr.v8i2.18894
Abstract
噪声污染作为全球第二大环境健康风险因素，对心血管系统的潜在致病机制涉及多维度病理过程。本研究系统性整合噪声暴露与心血管疾病的流行病学关联，从职业噪声暴露的剂量-效应关系及多因素联合暴露的协同效应出发，深度解析神经内分泌失调、氧化应激、血管内皮功能紊乱及睡眠障碍等核心致病通路。尽管现有证据支持噪声作为心血管疾病独立危险因素的假设，但其分子机制的系统性整合及暴露评估标准化仍需进一步探索。未来研究应聚焦噪声应激的表观遗传调控、单细胞水平的细胞谱系响应及智能监测技术的应用，以期为噪声相关心血管疾病的精准预防与干预提供理论依据。
Keywords
噪声暴露；心血管疾病；氧化应激；睡眠障碍；剂量-效应关系
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[29] 蒋斌杰,朱素娟.噪声与高温联合作用对劳动者心血管系统的影响[J].职业卫生与病伤,2022,37(4):199-201+207.
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[31] 陈樱,马建茹,郭军红,等.安阳某炼钢厂高温与噪声混合作业人员血压及心电图检测结果分析[J].中国卫生工学,2022,21(2):194-197.
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[33] She X, Gao X, Wang K, et al. Effects of noise and low-concentration carbon monoxide exposure on rat immunity[J]. J Occup Health. 2021;63(1):e12235. 5
[34] Li Y, Zhang Z, Wang J, et al. Effects and possible mechanisms of combined exposure to noise and carbon monoxide on male reproductive system in rats[J]. Environ Toxicol. 2023;38(12):2926-2938.
[35] Sørensen M, Poulsen AH, Nøhr B, et al. Long term exposure to road traffic noise and air pollution and risk of infertility in men and women: nationwide Danish cohort study[J]. BMJ. 2024;386:e080664. Published 2024 Sep 4.
[36] Tang JH, Jian HL, Chan TC. The impact of co-exposure to air and noise pollution on the incidence of metabolic syndrome from a health checkup cohort[J]. Sci Rep. 2024;14(1):8841. Published 2024 Apr 17.
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[38] Zhang Y, Liu C, Liu J, et al. Multi-omics reveals response mechanism of liver metabolism of hybrid sturgeon under ship noise stress[J]. Sci Total Environ. 2022;851(Pt 2):158348.
[39] Kvandova M, Filippou K, Steven S, et al. Environmental aircraft noise aggravates oxidative DNA damage, granulocyte oxidative burst and nitrate resistance in Ogg1-/- mice[J]. Free Radic Res. 2020;54(4):280-292.
[40] Daiber A, Frenis K, Kuntic M, et al. Redox Regulatory Changes of Circadian Rhythm by the Environmental Risk Factors Traffic Noise and Air Pollution[J]. Antioxid Redox Signal. 2022;37(10-12):679-703.
[41] Wu S, Du W, Wu Z, et al. Effect of chronic noise exposure on glucose and lipid metabolism in mice via modulating gut microbiota and regulating CREB/CRTC2 and SREBP1/SCD pathway[J]. Ecotoxicol Environ Saf. 2024;270:115887.
[42] Kröller-Schön S, Daiber A, Steven S, et al. Crucial role for Nox2 and sleep deprivation in aircraft noise-induced vascular and cerebral oxidative stress, inflammation, and gene regulation[J]. Eur Heart J. 2018;39(38):3528-3539.
[43] Argacha JF, Mizukami T, Bourdrel T, Bind MA. Ecology of the cardiovascular system: Part II - A focus on non-air related pollutants[J]. Trends Cardiovasc Med. 2019;29(5):274-282.
[44] 张远凤,叶清林,蒋晓江.噪声污染环境下失眠患者的临床睡眠及心理特征变化[C]//中国睡眠研究会.中国睡眠研究会第十五届全国学术年会汇编.陆军军医大学大坪医院;重庆西区医院;,2023:474.
[45] 吴静涵,董恺奕,郭立哲,等.老年人群睡眠障碍与心血管健康关系的研究进展[J].中南医学科学杂志,2022,50(1):137-140.
[46] Cho S, Park WJ, Ahn JS, Lim DY, Kim SH, Moon JD. Obstructive sleep apnea risk and hearing impairment among occupational noise-exposed male workers[J]. Arch Environ Occup Health. 2023;78(2):108-117.
[47] Bartoskova Polcrova A, Dalecka A, Szabo D, et al.Social and environmental stressors of cardiometabolic health[J]. Sci Rep. 2024;14(1):14179. Published 2024 Jun 19.
[48] 潘乐,汪翔,龚惠.单细胞测序在心血管系统中的应用[J].心血管病学进展,2020,41(12):1227-1230+1267.
[2] Golbidi S, Li H, Laher I. Oxidative Stress: A Unifying Mechanism for Cell Damage Induced by Noise, (Water-Pipe) Smoking, and Emotional Stress-Therapeutic Strategies Targeting Redox Imbalance[J]. Antioxid Redox Signal. 2018;28(9):741-759.
[3] Ossicini A, Mortara V, Goggiamani A. Evoluzione Legislativa della patologia da rumore: denunce ai fini assicurativi eprevenzionali a 20 anni dal D.Lgs 277/1991[J]. G Ital Med Lav Ergon 2011; 33:88-9.
[4] Maschke C. Cardiovascular effects of environmental noise: Research in Germany. Noise Health 2011; 13:205-11.
[5] Stansfeld S, Crombie R. Cardiovascular effects of environmental noise: research in the United Kingdom. Noise Health 2011; 13(52):229-33.
[6] 谢子煌,陈卫红.印刷行业职业病危害因素及其健康影响[J].职业卫生与应急救援,2017,35(6):530-532+563.
[7] 周静东,张晋蔚,周浩,等.广州市汽车制造企业男性电焊作业工人健康状况调查[J].职业卫生与应急救援,2017,35(3):227-230.
[8] Zhang A, Zou T, Guo D, et al. The Immune System Can Hear Noise[J]. Front Immunol. 2021;11:619189.
[9] Lee S, Lee Y, Lee W, et al. Environmental noise exposure and autoimmune diseases: Evidence from a national cohort study[J]. Ecotoxicol Environ Saf.2025;289:117674.
[10] Sivakumaran K, Ritonja JA, Waseem H, et al. Impact of Noise Exposure on Risk of Developing Stress-Related Health Effects Related to the Cardiovascular System: A Systematic Review and Meta-Analysis[J]. Noise Health. 2022;24(114):107-129.
[11] 周鹏飞,张舒,石菲,等.高血压与听力损失相互作用机制的研究进展[J].心脏杂志,2024,36(6):681-685.
[12] 胡凤霞,宋彬,易成,等.噪声对工人听力损失、血压、血糖和血脂的影响[J].工业卫生与职业病,2023,49(4):342-345.
[13] Li W, Zhang H, Xiao Y, Tao Y, Chen W, Wang D. Association between occupational noise exposure duration and heart rate variability among Chinese adults: The role of plasma miRNAs[J]. Environ Pollut. 2023;323:121324.
[14] 樊树利,赵慧,王剑伟,等.职业性噪声接触作业工人心血管及血脂异常的分析[J].工业卫生与职业病,2023,49(6):522-526.
[15] 庞振军,陆爱舟.企业生产性噪声对作业工人听力与心血管系统影响的分析[J].上海医药,2019,40(18):57-59.
[16] 赵文静,邹朝双.职业性噪声对作业人员听力和心血管系统影响[J].职业卫生与应急救援,2018,36(3):227-229.
[17] 汪琳,王春芳,张庆玲.噪声对工人听力损伤和其他健康影响的调查[J].工业卫生与职业病,2018,44(3):195-197.
[18] 周军,郝晓凤,李新刚.噪声对纺织工人健康影响调查[J].中国城乡企业卫生,2018,33(9):81-82.
[19] 蔡芳芳,李俊,严琨,等.噪声对心血管系统相关指标影响的分析[J].贵阳中医学院学报,2017,39(6):60-63.
[20] 覃剑丁,陈晓华,李妍,等.柳州市某钢铁企业噪声对作业工人健康损害的情况分析[J].职业与健康,2022,38(7):879-882+887.
[21] 钟松更,刘常林,郑艳芳.8713名噪声作业人员职业健康检查结果分析[J].中国卫生工程学,2023,22(6):766-769+771.
[22] 陈哲玮,丰薇薇.2019年肇庆市噪声作业工人听觉系统和心血管系统异常情况分析[J].中国社区医师,2023,39(24):152-154.
[23] 李秀婷,赵亮亮,董秋,等.南京市噪声作业人群职业健康检查结果分析[J].中国预防医学杂志,2019,20(4):285-289.
[24] 王淼,刘涛,曾强.职业性噪声对工人心血管系统影响研究进展[J].中国职业医学,2022,49(6):707-711.
[25] 周晓,薛鹏程.挂车制造行业噪声对作业工人听力和心血管系统影响调查[J].应用预防医学,2021,27(5):439-441.
[26] 李庆猛,朱安宁.2017年蚌埠市噪声作业工人职业健康检查结果分析[J].工业卫生与职业病,2020,46(2):148-149.
[27] Wang Z, Qian R, Xiang W, et al. Association between noise exposure during pregnancy and pregnancy complications: A meta-analysis[J]. Front Psychol. 2022;13:1026996. Published 2022 Nov 21.
[28] Graafland N, Essers E, Posthumus A, et al. Exposure to outdoor residential noise during pregnancy, embryonic size, fetal growth, and birth outcomes[J]. Environ Int. 2023;171:107730.
[29] 蒋斌杰,朱素娟.噪声与高温联合作用对劳动者心血管系统的影响[J].职业卫生与病伤,2022,37(4):199-201+207.
[30] 徐紫菡,戴冬梅,高娇娇,等.职业噪声和高温对心血管系统的影响[J].中华疾病控制杂志,2020,24(7):773-778.
[31] 陈樱,马建茹,郭军红,等.安阳某炼钢厂高温与噪声混合作业人员血压及心电图检测结果分析[J].中国卫生工学,2022,21(2):194-197.
[32] Wang D, Wang Z, Zhou M, et al. The combined effect of cigarette smoking and occupational noise exposure on hearing loss: evidence from the Dongfeng-Tongji Cohort Study[J]. Sci Rep. 2017;7(1):11142. Published 2017 Sep 11.
[33] She X, Gao X, Wang K, et al. Effects of noise and low-concentration carbon monoxide exposure on rat immunity[J]. J Occup Health. 2021;63(1):e12235. 5
[34] Li Y, Zhang Z, Wang J, et al. Effects and possible mechanisms of combined exposure to noise and carbon monoxide on male reproductive system in rats[J]. Environ Toxicol. 2023;38(12):2926-2938.
[35] Sørensen M, Poulsen AH, Nøhr B, et al. Long term exposure to road traffic noise and air pollution and risk of infertility in men and women: nationwide Danish cohort study[J]. BMJ. 2024;386:e080664. Published 2024 Sep 4.
[36] Tang JH, Jian HL, Chan TC. The impact of co-exposure to air and noise pollution on the incidence of metabolic syndrome from a health checkup cohort[J]. Sci Rep. 2024;14(1):8841. Published 2024 Apr 17.
[37] Hurtado CV, Dongil P, Pérez GA, Álvarez E, Sanz C. Preventing Oxidative Stress in the Liver: An Opportunity for GLP-1 and/or PASK[J]. Antioxidants (Basel). 2021; 10(12):2028.
[38] Zhang Y, Liu C, Liu J, et al. Multi-omics reveals response mechanism of liver metabolism of hybrid sturgeon under ship noise stress[J]. Sci Total Environ. 2022;851(Pt 2):158348.
[39] Kvandova M, Filippou K, Steven S, et al. Environmental aircraft noise aggravates oxidative DNA damage, granulocyte oxidative burst and nitrate resistance in Ogg1-/- mice[J]. Free Radic Res. 2020;54(4):280-292.
[40] Daiber A, Frenis K, Kuntic M, et al. Redox Regulatory Changes of Circadian Rhythm by the Environmental Risk Factors Traffic Noise and Air Pollution[J]. Antioxid Redox Signal. 2022;37(10-12):679-703.
[41] Wu S, Du W, Wu Z, et al. Effect of chronic noise exposure on glucose and lipid metabolism in mice via modulating gut microbiota and regulating CREB/CRTC2 and SREBP1/SCD pathway[J]. Ecotoxicol Environ Saf. 2024;270:115887.
[42] Kröller-Schön S, Daiber A, Steven S, et al. Crucial role for Nox2 and sleep deprivation in aircraft noise-induced vascular and cerebral oxidative stress, inflammation, and gene regulation[J]. Eur Heart J. 2018;39(38):3528-3539.
[43] Argacha JF, Mizukami T, Bourdrel T, Bind MA. Ecology of the cardiovascular system: Part II - A focus on non-air related pollutants[J]. Trends Cardiovasc Med. 2019;29(5):274-282.
[44] 张远凤,叶清林,蒋晓江.噪声污染环境下失眠患者的临床睡眠及心理特征变化[C]//中国睡眠研究会.中国睡眠研究会第十五届全国学术年会汇编.陆军军医大学大坪医院;重庆西区医院;,2023:474.
[45] 吴静涵,董恺奕,郭立哲,等.老年人群睡眠障碍与心血管健康关系的研究进展[J].中南医学科学杂志,2022,50(1):137-140.
[46] Cho S, Park WJ, Ahn JS, Lim DY, Kim SH, Moon JD. Obstructive sleep apnea risk and hearing impairment among occupational noise-exposed male workers[J]. Arch Environ Occup Health. 2023;78(2):108-117.
[47] Bartoskova Polcrova A, Dalecka A, Szabo D, et al.Social and environmental stressors of cardiometabolic health[J]. Sci Rep. 2024;14(1):14179. Published 2024 Jun 19.
[48] 潘乐,汪翔,龚惠.单细胞测序在心血管系统中的应用[J].心血管病学进展,2020,41(12):1227-1230+1267.
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