乙肝相关性肝癌微血管侵犯风险预测模型的系统评价
Journal: Basic Medical Theory Research DOI: 10.32629/bmtr.v8i1.18543
Abstract
目的：检索和评价现有的乙肝相关性肝癌患者微血管侵犯风险预测模型,旨在为构建更高质量的风险预测模型提供参考。方法：检索中国知网、万方数据库、中国生物医学文献数据库、PubMed、Web of Science、Embase中有关乙肝相关性肝癌患者微血管侵犯风险预测模型构建的研究,检索时限为建库至2024年1月15日,由2名研究者独立筛选文献,根据CHARMS进行资料提取,采用PROBAST偏倚评估工具对纳入的风险预测模型进行评价。结果：共纳入7项研究,甲胎蛋白、肿瘤直径为最常见独立预测因子；模型偏倚风险高多为回顾性研究等,AUC为0.684-0.930。结论：现有模型尚处发展阶段,影响因素有争议,偏倚高且缺乏验证。
Keywords
乙型肝炎；肝癌；微血管侵犯；预测模型；系统评价
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