Primary hemangiopericytoma of the lung as an incidental finding: report of two cases
Journal: Advances in Medicine and Engineering Interdisciplinary Research DOI: 10.32629/ameir.v4i2.5256
Abstract
Intrapulmonary hemangiopericitoma potentially is a rare malignancy, which originates from the pericytes that surround the basal membrane of the capillaries and venules in lung parenchyma. Objective: The aim is to present two cases as an incidental finding in its presentation and also know the behavior and management of this neoplasm. Clinical cases: A male patient of 40 years with clinical picture characterized by persistent dry cough, fatigue with shortness of breath with rapid progression to small effort dyspnea and weight loss and a female patient aged 37 clinical picture characterized by chest pain oppressive kind in lateral region posterior right chest, radiating to the shoulder in the chest film, multiple nodular parenchymal bilateral central and sub-pleural. The second patient so poster anterior chest radiograph where a pattern of tumor mass located in the center of the right lung, which was confirmed by computed tomography of the chest, is observed is performed. In the patient he proceeded to the surgical recession of the injury to biopsy, while in the female patient's behavior was more radical right pneumonectomy was practical. They are evolving satisfactorily. Report biopsy and immunohistochemistry for primary lung: Hemangiopericitoma / SFT. Both patients were referred to medical oncology service for adjuvant therapy. Conclusion: Is a rare tumor, its pathogenesis is still unknown and although a tumor in appearance and benign behavior, should be treated as malignant potential, must be radical in treatment and careful monitoring, continuous and strict patient.
Keywords
hemangiopericitoma; primary; lung; tumor; malignant
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[1] López Díaz JL, Pacheco Sánchez R, Tejedor Sánchez J. Cuadros JL, Vivanco Martínez D, Cabezalí BI, et al. Tumores broncopulmonares primarios. Cir Pediatr. 2006;19:223-227.
[2] Varela R, García HA, Cortés V. Testicular hemangiopericytoma, solitary fibrous tumor: A very rare case. Arch. Esp. Urol. 2010;63(9):816-819.
[3] Gengler C, Guillou L. Solitary fibrous tumor and haemangiopericytoma: Evolution of a concept. Histopathology. 2006;48:63-74.
[4] Montserrat J, Astudillo PJ, Teixidor S, Aguilera MJ, Oliveras E. Hemangiopericitoma pulmonar. Presentación de dos casos y revisión de la literatura. Arch Bronconeumol. 1990;26:320-323.
[5] Bedmar MD, Varela UC, Squella BG, Belletti BJ, Donoso MV. Hemangiopericitoma de aurícula izquierda: Caso clínico. Rev. méd Chile. 2011;139:770-773.
[6] Kuroya M, Yokomise H, Inui K, Ike O, Mizuno H, Wada H, et al. Resection of primary pulmonary hemangiopericytoma. A report of two cases. Surg Today. 1996;26:208-212.
[7] Villalba V, García R, Gilbert J, Salvador JL. Intestinal hemangiopericytoma. Cir Esp. 2005;77:48-50.
[8] Gac EP, Seymour MC, Klein PE, Cabané TP, Segura HP, Pruzzo GM. Hemangiopericitoma: Reporte de 3 casos. Rev Chil Cir. 2013;65(2):172-176.
[9] Hernández A, Padilla A, González R. Hemangiopericitoma de la glándula parótida: reporte de un caso. Anales médicos (México, DF). 2013:20;58(1):60-64.
[10] Patsios D, Hwang DM, Chung TB. Intraparenchymal solitary fibrous tumor of the lung: An uncommon cause of a pulmonary nodule. J orac Imaging. 2006;2(1):50-53.
[11] Sakurai H, Tanaka W, Kaji M, Yamazaki K, Suemasu K. Intrapulmonary localized fibrous tumor of the lung: A very unusual presentation. Ann Thorac Surg. 2008; 86:1360-1362.
[12] Gimenez A, Franquet T, Prats R, Estrada P, Villalba J, Bagué S. Unusual primary lung tumors: A radiologicpathologic overview. Radiographics. 2002;22:601-619.
[13] Sagawa M, Ueda Y, Matsubara F, Sakuma H, Yoshimitsu Y, Aikawa H, et al. Intrapulmonary solitary fibrous tumor diagnosed by immunohistochemically and genetic approaches: Report of a case. Surg Today. 2007;37:423-425.
[14] Rusch VW, Shuman WP, Schmidt R, Laramore GE. Massive pulmonary hemangiopericytoma. An innovative approach to the evaluation and treatment. Cancer 1989;64:1928-1936.
[15] Espat NJ, Lewis JJ, Leung D, Woodruff JM, Antonescu CR, Shia J, et al. Conventional hemangiopericytoma: Conventional hemangiopericytoma: Modern analysis of outcome. Cancer. 2002;95:1746-1751.
[16] Chnaris A, Barbetakis N, Efstathiou A, Fessatidis Y. Primary mediastinal hemangiopericytoma. World Journal of Surgical Oncology. 2006;4:4-23.
[2] Varela R, García HA, Cortés V. Testicular hemangiopericytoma, solitary fibrous tumor: A very rare case. Arch. Esp. Urol. 2010;63(9):816-819.
[3] Gengler C, Guillou L. Solitary fibrous tumor and haemangiopericytoma: Evolution of a concept. Histopathology. 2006;48:63-74.
[4] Montserrat J, Astudillo PJ, Teixidor S, Aguilera MJ, Oliveras E. Hemangiopericitoma pulmonar. Presentación de dos casos y revisión de la literatura. Arch Bronconeumol. 1990;26:320-323.
[5] Bedmar MD, Varela UC, Squella BG, Belletti BJ, Donoso MV. Hemangiopericitoma de aurícula izquierda: Caso clínico. Rev. méd Chile. 2011;139:770-773.
[6] Kuroya M, Yokomise H, Inui K, Ike O, Mizuno H, Wada H, et al. Resection of primary pulmonary hemangiopericytoma. A report of two cases. Surg Today. 1996;26:208-212.
[7] Villalba V, García R, Gilbert J, Salvador JL. Intestinal hemangiopericytoma. Cir Esp. 2005;77:48-50.
[8] Gac EP, Seymour MC, Klein PE, Cabané TP, Segura HP, Pruzzo GM. Hemangiopericitoma: Reporte de 3 casos. Rev Chil Cir. 2013;65(2):172-176.
[9] Hernández A, Padilla A, González R. Hemangiopericitoma de la glándula parótida: reporte de un caso. Anales médicos (México, DF). 2013:20;58(1):60-64.
[10] Patsios D, Hwang DM, Chung TB. Intraparenchymal solitary fibrous tumor of the lung: An uncommon cause of a pulmonary nodule. J orac Imaging. 2006;2(1):50-53.
[11] Sakurai H, Tanaka W, Kaji M, Yamazaki K, Suemasu K. Intrapulmonary localized fibrous tumor of the lung: A very unusual presentation. Ann Thorac Surg. 2008; 86:1360-1362.
[12] Gimenez A, Franquet T, Prats R, Estrada P, Villalba J, Bagué S. Unusual primary lung tumors: A radiologicpathologic overview. Radiographics. 2002;22:601-619.
[13] Sagawa M, Ueda Y, Matsubara F, Sakuma H, Yoshimitsu Y, Aikawa H, et al. Intrapulmonary solitary fibrous tumor diagnosed by immunohistochemically and genetic approaches: Report of a case. Surg Today. 2007;37:423-425.
[14] Rusch VW, Shuman WP, Schmidt R, Laramore GE. Massive pulmonary hemangiopericytoma. An innovative approach to the evaluation and treatment. Cancer 1989;64:1928-1936.
[15] Espat NJ, Lewis JJ, Leung D, Woodruff JM, Antonescu CR, Shia J, et al. Conventional hemangiopericytoma: Conventional hemangiopericytoma: Modern analysis of outcome. Cancer. 2002;95:1746-1751.
[16] Chnaris A, Barbetakis N, Efstathiou A, Fessatidis Y. Primary mediastinal hemangiopericytoma. World Journal of Surgical Oncology. 2006;4:4-23.
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