Chondroblastoma of the costal wall: a rare neoplastic phenomenon. case report and literature review
Journal: Advances in Medicine and Engineering Interdisciplinary Research DOI: 10.32629/ameir.v4i1.4931
Abstract
The chondroblastoma is a rare benign bone tumor that typically arises in the epiphysis. Few cases of rib chondroblastoma have been reported in the literature. Clinical case: We describe a case of a 46-year-old male patient with chondroblastoma located in the left anterior 7th rib. The high-resolution computed tomography demonstrated a tumor in the 7th costal rib, a well-defined oval lesion measuring 110 mm x 100 m x 59 mm in the transverse and the anteroposterior diameters, with an area of lytic bone destruction, with no evidence of tissue extension adjacent soft tissue. Although the costal chondroblastoma are very rare neoplasms, they should be included in the differential diagnosis when they are found with an aggressive costal mass and the histological confirmation should be performed. The biopsy was performed with a 14 G core needle of the tumor lesion. The pathological and immunohistochemical examination made the diagnosis of chondroblastoma. A systematic review of the literature was carried out which showed that the chondroblastoma can affect people of all ages, but it is more common in children and young adults. Despite the patient not having had surgery, the surgical resection is the treatment of choice. Conclusion: The costal chondroblastomas are very rare and appear to be aggressive on imaging findings; with soft tissue extension, thin sclerotic border and the bone destruction.
Keywords
rib; chondroblastoma; bone tumor; biopsy; tomography
Full Text
PDF - Viewed/Downloaded: 0 TimesReferences
[1] Herrera-Rodríguez M, Miranda-Chavarría J. Tumores cortados torácica. Acta med. costarricense [Internet]. Marzo de 2003;45(Suplemento1):33-34. Disponible en: URL: https://www.scielo.sa.cr/scielo.php?script=sci_arttext&pid=S0001 60022003000500005&lng=en.
[2] Focaccia M, Gambarotti M, Hakim R, Paioli A, Cesari M, Spazzoli B, et al. Chondroblastoma's lung metastases treated with denosumab in pediatric patient. Cancer Res Treat. 2021;53(1):279-282.
[3] Hernández E, Barrios N, Rodas J, Claverie-Martínez G, Rodas-Pernillo O. Condroblastoma del hueso calcáneo: un caso inusual. Rev. méd. (Col. Méd. Cir. Guatem.). 2022;161(3):312-314. Disponible en: URL: https://www.revistamedicagt.org/index.php/RevMedGuatemala/article/view/517/888.
[4] Lang Y, Yu Q, Liu Y, Yang L. Chondroblastoma of the patella with pathological fracture in an adolescent: A case report. World J Surg Oncol. 2019;17(1):218.
[5] Long L, Li Z, Tang Y. Chondroblastoma in the sphenoid sinus. Ear Nose Throat J. 2021;100(10_Suppl):1139S-1140.
[6] Rizo Fiallo Y, Tamayo Figueroa A, Morales A, Ismael A. Condroblastoma de tercio proximal de húmero derecho. Revista Cubana de Ortopedia y Traumatología. 2021;35(3):e263. Disponible en: URL: https:// revortopedia.sld.cu/index.php/revortopedia/article/view/263/294.
[7] Oyanedel QR, García BC, Villanueva AE, Otero J, Solar GA, Rojas CR, et al .Estudio radiológico simple en el diagnóstico de condroblastoma epifisiario benigno: correlación anatomo - radiológica. Rev. chil. radiol. [revista en la Internet]. 2007;13(4):185-190. Disponible en: URL: https://www.scielo.cl/scielo.php? script=sci_arttext&pid=S0717-93082007000400003.
[8] Ferreres-Claramunt Á, Lázaro L. Condroblastomas del carpo: caso clínico y revisión de la literatura. Disponible en: URL: https://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0038-1667321.pdf.
[9] Jundt G, Baumhoer D. Chondroblastoma. Pathologe. 2018;39(2):132-138.
[10] Hmada YA, Bernieh A, Morris RW, Lewin J, Allen T. Chondroblastoma-like osteosarcoma. Arch Pathol Lab Med. 2020;144:15-17.
[11] Rekhi B, Ghate S, Shah A, Ramadwar M, Gulia A. Immunohistochemical analysis of 36 cases of chondroblastomas: A single institutional experience. Ann Diagn Pathol. 2020; 44:151440.
[12] Xiong Y, Lang Y, Yu Z, Liu H, Fang X, Tu C, et al. The effects of surgical treatment with chondroblastoma in children and adolescents in open epiphyseal plate of long bones. World J Surg Oncol. 2018;16(1):14.
[13] Chen W, DiFrancesco LM. Chondroblastoma. An Update. Arch Pathol Lab Med. 2017; 141:867-871.
[14] Cortés RR, Lezama VP, Lugo B, Fuentes V. Condroblastoma benigno. Manejo quirúrgico con endoprótesis tumoral tibial no convencional RC-9. Arch Inv Mat Inf. 2019;10(2):43-49.
[15] Venkatasamy A, Chenard M, Massard G, Steib J, Bierry G. Chondroblastoma of the thoracic spine: A rare location: A case report with radiologic-pathologic correlation. Skeletal Radiol. 2017;46(3):367-372.
[16] Brandolini J, Bertolaccini L, Pardolesi A, Salvi M, Valli M, Solli P. Chondroblastoma of the rib in a 47-year-old man: A case report with a systematic review of literature. J Thorac Dis. 2017;9(10):E907-E11.
[17] Wu Y, Guan J, Kai Z, Huiguo C, Wu W, Zhang J. Rare chondroblastoma of the 6th left rib, video-assisted thoracoscopy resected: One case report and literature review. J Cardiothorac Surg. 2021;16(1):192.
[18] Wu CT, Chen ACY, Wang CJ, Wang CW, Fu CJ, Wong YC. Chondroblastoma of the triquetrum. Pediatr Neonatol. 2013;54(04):278-280.
[19] Clapper AT, DeYoung BR. Chondroblastoma of the femoral diaphysis: Report of a rare phenomenon and review of literature. Hum Pathol. 2007;38(5):803-806.
[2] Focaccia M, Gambarotti M, Hakim R, Paioli A, Cesari M, Spazzoli B, et al. Chondroblastoma's lung metastases treated with denosumab in pediatric patient. Cancer Res Treat. 2021;53(1):279-282.
[3] Hernández E, Barrios N, Rodas J, Claverie-Martínez G, Rodas-Pernillo O. Condroblastoma del hueso calcáneo: un caso inusual. Rev. méd. (Col. Méd. Cir. Guatem.). 2022;161(3):312-314. Disponible en: URL: https://www.revistamedicagt.org/index.php/RevMedGuatemala/article/view/517/888.
[4] Lang Y, Yu Q, Liu Y, Yang L. Chondroblastoma of the patella with pathological fracture in an adolescent: A case report. World J Surg Oncol. 2019;17(1):218.
[5] Long L, Li Z, Tang Y. Chondroblastoma in the sphenoid sinus. Ear Nose Throat J. 2021;100(10_Suppl):1139S-1140.
[6] Rizo Fiallo Y, Tamayo Figueroa A, Morales A, Ismael A. Condroblastoma de tercio proximal de húmero derecho. Revista Cubana de Ortopedia y Traumatología. 2021;35(3):e263. Disponible en: URL: https:// revortopedia.sld.cu/index.php/revortopedia/article/view/263/294.
[7] Oyanedel QR, García BC, Villanueva AE, Otero J, Solar GA, Rojas CR, et al .Estudio radiológico simple en el diagnóstico de condroblastoma epifisiario benigno: correlación anatomo - radiológica. Rev. chil. radiol. [revista en la Internet]. 2007;13(4):185-190. Disponible en: URL: https://www.scielo.cl/scielo.php? script=sci_arttext&pid=S0717-93082007000400003.
[8] Ferreres-Claramunt Á, Lázaro L. Condroblastomas del carpo: caso clínico y revisión de la literatura. Disponible en: URL: https://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0038-1667321.pdf.
[9] Jundt G, Baumhoer D. Chondroblastoma. Pathologe. 2018;39(2):132-138.
[10] Hmada YA, Bernieh A, Morris RW, Lewin J, Allen T. Chondroblastoma-like osteosarcoma. Arch Pathol Lab Med. 2020;144:15-17.
[11] Rekhi B, Ghate S, Shah A, Ramadwar M, Gulia A. Immunohistochemical analysis of 36 cases of chondroblastomas: A single institutional experience. Ann Diagn Pathol. 2020; 44:151440.
[12] Xiong Y, Lang Y, Yu Z, Liu H, Fang X, Tu C, et al. The effects of surgical treatment with chondroblastoma in children and adolescents in open epiphyseal plate of long bones. World J Surg Oncol. 2018;16(1):14.
[13] Chen W, DiFrancesco LM. Chondroblastoma. An Update. Arch Pathol Lab Med. 2017; 141:867-871.
[14] Cortés RR, Lezama VP, Lugo B, Fuentes V. Condroblastoma benigno. Manejo quirúrgico con endoprótesis tumoral tibial no convencional RC-9. Arch Inv Mat Inf. 2019;10(2):43-49.
[15] Venkatasamy A, Chenard M, Massard G, Steib J, Bierry G. Chondroblastoma of the thoracic spine: A rare location: A case report with radiologic-pathologic correlation. Skeletal Radiol. 2017;46(3):367-372.
[16] Brandolini J, Bertolaccini L, Pardolesi A, Salvi M, Valli M, Solli P. Chondroblastoma of the rib in a 47-year-old man: A case report with a systematic review of literature. J Thorac Dis. 2017;9(10):E907-E11.
[17] Wu Y, Guan J, Kai Z, Huiguo C, Wu W, Zhang J. Rare chondroblastoma of the 6th left rib, video-assisted thoracoscopy resected: One case report and literature review. J Cardiothorac Surg. 2021;16(1):192.
[18] Wu CT, Chen ACY, Wang CJ, Wang CW, Fu CJ, Wong YC. Chondroblastoma of the triquetrum. Pediatr Neonatol. 2013;54(04):278-280.
[19] Clapper AT, DeYoung BR. Chondroblastoma of the femoral diaphysis: Report of a rare phenomenon and review of literature. Hum Pathol. 2007;38(5):803-806.
Copyright © 2026 Juan Carlos Araujo-Cuauro, Milagros Sánchez De Rosales
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License