Oral manifestations of Crohn's disease and ulcerative colitis in of elderly adults
Journal: Advances in Medicine and Engineering Interdisciplinary Research DOI: 10.32629/ameir.v4i1.4930
Abstract
Objective: Identify the oral clinical manifestations of Crohn's disease and ulcerative colitis in elderly adults’ patients. Methods: A cross-sectional descriptive study was carried out with a universe of 50 older adults previously diagnosed by gastroenterologist specialists, prescribing the presence of Crohn's disease and ulcerative colitis, confirmed by clinical, histopathological and endoscopic findings, referred to the stomatological consultation of the Specialities Policlinic of the "Saturnino Lora Torres" University Clinical Surgical Hospital of Santiago de Cuba, from March 2019 to the same month of 2020, performing intraoral examination, description of oral lesions and their clinical diagnosis. For the collection of the primary data, a model was made with the variables: age, sex, inflammatory bowel disease, anatomical location, oral clinical signs and symptoms in both pathologies. A database was created in SPSS version 22.0 in Windows for the processing and analysis of the information, using the descriptive statistical technique and grouping the data in absolute and relative frequencies. Results: In the casuistry, females and the age group of 60 to 74 years prevailed, vegetative pyostomatitis was the most common specific oral sign and recurrent aphthous ulcer was the most prevalent non-specific lesion in both pathologies, pain being the most affecting clinical symptom and the back of the tongue is the most preferred site for its installation. Conclusions: The most relevant oral clinical expressions in elderly patients adults with Crohn's disease and ulcerative colitis were pyostomatitis vegetative and recurrent aphthous ulcer.
Keywords
inflammatory bowel diseases; Crohn's disease; ulcerative colitis; oral manifestations; pyostomatitis vegetans; recurrent aphthous ulcer
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[3] Rodríguez-Casas MM, Hernández-Falcón L, Garay-Crespo MI, Castillo-Mateu L. Cambios morfológicos en el sistema estomatognático del adulto mayor, aspectos de interés para la Atención Estomatológica Integral. Anatomía Digital. 2021; 4(1): 6–16. https://doi.org/10.33262/anatomiadigital.v4i1.1477.
[4] Sbeit W, Kadah A, Mahmud-Mahamid M, Hala-Karayanni H, Mari A, Tali T, et al. Oral manifestations of inflammatory bowel disease: the forgotten piece of the puzzle. Eur J Gastroenterol Hepatol. 2020; 32(11): 1422-1431. https://doi.org/10.1097/MEG.0000000000001918.
[5] Jajam M, Bozzolo P, Niklander S. Oral manifestations of gastrointestinal disorders. J Clin Exp Dent. 2017; 9(10): e1242–e1248. https://doi.org/10.4317/jced.54008.eCollection 2017.
[6] Sevilla-García RM. Manifestaciones orales de la enfermedad inflamatoria intestinal [Trabajo de grado para optar al título de odontóloga]. Sevilla: Universidad de Sevilla; 2019. Disponible en: https://idus.us.es/bitstream/ handle/11441/104242/.
[7] Melero-Alarcón C, Montañés-de la Fuente A, Solís-González S, Grande-Boloque R, Peña-Cardelles JF, Paredes-Rodríguez VM, et al. Manejo y consideraciones clínicas de la enfermedad inflamatoria intestinal en la consulta dental. Rev Cient Dent. 2018; 15(1): 31-35. Disponible en: https://coem. org.es/pdf/publicaciones/ cientifica/vol15num1/5enfermedadintestinal.pdf; https://pesquisa.bvsalud.org/ /resource/pt/ibc-172858.
[8] Oviedo-Yañez CM, Pennacchiotti V. Frecuencia de manifestación oral en pacientes con enfermedad inflamatoria intestinal en Chile. Int J Odontostomat. 2017; 11(3): 267-271. Disponible en: https://scielo.conicyt.cl/scielo.php?script=sci-arttext&pid= S0718 381X20170003 00267&lng=es.
[9] Crowley E, Muise A. Inflammatory Bowel Disease: what very early onset disease teaches us. Gastroenterol Clin North Am. 2018; 47(4): 755-772. https://doi.org/10.1016/j.gtc.2018.07.004.
[10] Figueroa C. Epidemiología de la enfermedad inflamatoria intestinal. Rev Med Clin Condes. 2019; 30(4): 257-261. https://doi.org/10.1016/j.rmclc.2019.06.003.
[11] Lauritano D, Boccalari E, Di Stasio D, Della F, Carini F, Lucchese A, et al. Prevalence of oral lesions and correlation with intestinal symptoms of inflammatory bowel disease: A systematic review. Diagnostics (Basel). 2019; 9(3): 77. https://doi.org/10.3390/diagnostics9030077.
[12] Thomas C, Dimmock M, Gilletta de Saint-Joseph C, Barres-Paul C, Cousty S, Laurencin-Dalicieux S. How Oral Specialists Can Help Diagnose and Manage Extra-Digestive Inflammatory Bowel Disease Complications. Case Rep Gastroenterol. 2021; 15(1): 276-281. https://doi.org/10.1159/000513156.
[13] Ruiz-Sáenz P, Sanz-Alonso J, Buesa-Barez J, Martínez-Rodríguez N, Martínez-González JM. Consideraciones en Cirugía Bucal de los pacientes con enfermedad de Crohn. Cient Dent. 2018; 15(1): 61-67. Disponible en: https://coem.org.es/ pdf/publicaciones/cientifica/vol15num1/9 Crohn. Pdf.
[14] Tan CXW, de Boer NKH, Brand HS. Oral manifestations of Crohn disease. Ned Tijdschr Tandheelkd. 2018; 125(1): 15–20. https://doi.org/10.5177/ntvt.2018.01.17174.
[15] Giuseppe-Ribaldone D, Brigo S, Mangia M, Saracco GM, Astegiano M, Pellicano R. Oral Manifestations of Inflammatory Bowel Disease and the Role of Non-Invasive Surrogate Markers of Disease Activity. Medicines. 2020; 7(6): 33. https://doi.org/10.3390/medicines7060033.
[16] Khozeimeh F, Shakerin H, Daghaghzadeh H, Najarzadegan F, Golestannejad Z, Adibi P. Oral manifestations in inflammatory bowel disease: A cross-sectional study in Isfahan. Dent Res J (Isfahan). 2021; 18(4). Disponible en: https://pubmed.ncbi.nlm.nih.gov/34084291/.
[17] Antonelli E, Maconi G, Bassotte G, Tramontana M, Hansel K, Stingeni L, et al. Dermatological manifestations in inflammatory bowel diseases. J Clin Med. 2021; 10(2): 364. Disponible en: https://www.mdpi.com/ 2077-0383/10/2/364/htm/.
[18] Bader F, Al-Safadi A. Inflammatory Bowel Disease and Oral Health: A Review of Dental Consideration. Saudi J Oral Dent Res. 2020; 7(6): 165-168. https://doi.org/10.36348/sjodr.2022.v07i06.004.
[19] Mortada I, Leone A, Gerges-Geagea A, Mortada R, Matar C, Rizzo M, et al. Oral manifestations of inflammatory bowel disease. J Biol Regul Homeost Agent. 2017; 31(3): 817-821.Disponible en: https://pubmed.ncbi.nlm.nih.gov/28958141/.
[20] Mohan-Kumar KP, Nachiammai N, Madhushankari GS. Association of oral manifestations in ulcerative colitis. A pilot study. J Oral Maxillofac Pathol. 2018; 22(2): 199-203. https://doi.org/10.4103/jomfp.JOMFP-223-16.
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