A Meta-analysis of the Incidence of Frailty and its Influencing Factors in Middle-aged and Elderly Inpatients with Hypertension
Journal: Advanced Journal of Nursing DOI: 10.32629/ajn.v5i4.3244
Abstract
Objective: To systematically review the current status of frailty and its influencing factors in middle-aged and-elderly patients hospitalized with hypertension. Methods: Literature of CNKI, China Science and Technology Journal Database, Wanfang, PubMed, Embase, Medline, Web of Science and Cochrane Library on the factors affecting combined frailty in middle-aged and elderly hypertensive patients were searched to build the database until December 31, 2023, and Meta-analysis was conducted using RevMan5.4 software. Results: A total of 14 articles including 4097 middle-aged and elderly hypertensive patients were included. The Meta-analysis results showed that: The incidence of frailty in the middle-aged and elderly hypertensive patients was 36%. And A total of 13 contributing factors were statistically significant (P <0.05). Conclusion: The occurrence of frailty in middle-aged and elderly hypertensive hospitalized patients is affected by many factors. Medical staff should focus on the evaluation and management of high-risk groups, and make early intervention to reduce the occurrence of frailty and slow down the process of frailty.
Keywords
hypertension, frailty, influencing factor, meta-analysis
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[30]Xi Xing, Guo Guifang. Study on the current status of the community elderly and its influencing factors [J]. Nursing Management in China, 2014,14 (12): 1315-1319.
[31]Dent, E et al. “Use of the Mini Nutritional Assessment to detect frailty in hospitalised older people.” The journal of nutrition, health & aging vol. 16,9 (2012): 764-7. doi:10.1007/s12603-012-0405-5
[32]Li Yongle. Study on the relationship between body mass index, lipid metabolism level and frailty in elderly inpatients with hypertension [D]. North China University of Science and Technology, 2019.
[2]Chen Juan, Xie Jinan, Ye Kui, et al. Investigation and analysis of the prevalence of hypertension among urban and rural residents aged 15 years and above in Hefei city [J]. Chinese Journal of Disease Prevention and Control,2016,20(4):366-369.
[3]China Revision Guidelines for Hypertension, Hypertension Alliance (China), Hypertension Society of Hypertension, China Association for International Promotion of Medical Care Exchange, etc. Chinese Guidelines for the Prevention and Treatment of Hypertension (revised in 2024) [J]. Chinese Journal of Hypertension (Chinese and English), 2024,32(07):603-700.DOI:10.16439/j.issn.1673-7245.2024.07.002.
[4]Fried, L P et al. “Frailty in older adults: evidence for a phenotype.” The journals of gerontology. Series A, Biological sciences and medical sciences vol. 56,3 (2001): M146-56. doi:10.1093/gerona/56.3.m146
[5]Aprahamian I, Sassaki E, Dos Santos MF, Izbicki R, Pulgrossi RC, Biella MM, Borges ACN, Sassaki MM, Torres LM, Fernandez ÍS, Pião OA, Castro PLM, Fontenele PA, Yassuda MS. Hypertension and frailty in older adults. J Clin Hypertens (Greenwich). 2018 Jan;20(1):186-192. doi: 10.1111/jch.13135. Epub 2017 Nov 5. PMID: 29105991; PMCID: PMC8031203.
[6]Ma, Lina et al. “Epidemiological characteristics and related factors of frailty in older Chinese adults with hypertension: a population-based study.” Journal of hypertension vol. 38,11 (2020): 2192-2197. doi:10.1097/HJH.0000000000002650
[7]Wang Xibo. The occurrence of frailty and its correlation with the constitution index [J]. Guangxi Medical, 2019,41 (17): 2249-2250 + 2261.
[8]Chen Yuping, Zhang Xiangeng, Cao Jun, et al. Status and influencing factors in elderly hypertensive patients in the community [J]. Chinese Journal of Gerontology, 2022,42 (02): 459-462.
[9]Kunjie Liu, Sun Yanhong, Jiang Li, et al. Analysis of the influencing factors of frailty in elderly hypertensive patients [J]. Practical Geriatrics, 2022,36 (01): 89-90 + 94.
[10]Hu K, Zhou Q, Jiang Y, Shang Z, Mei F, Gao Q, Chen F, Zhao L, Jiang M, Ma B. Association between Frailty and Mortality, Falls, and Hospitalization among Patients with Hypertension: A Systematic Review and Meta-Analysis. Biomed Res Int. 2021 Jan 27;2021:2690296. doi: 10.1155/2021/2690296. PMID: 33575325; PMCID: PMC7861941.
[11]Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of non-randomized studies in meta-analyses[J]. European journal of epidemiology, 2010, 25: 603-605.
[12]Zeng Xiantao, Liu Hui, Chen Xi, et al. Meta-analysis series IV: A Quality Assessment Tool for Observational Studies [J]. Chinese Journal of Evidence-Based Cardiovascular Medicine, 2012,4 (4): 297-299. DOI:10.3969/j.1674-4055.2012.04.004.
[13]Can Zhao, Liu Shanshan, Li Jingbing, et al. Exploring the incidence of frailty syndrome and related risk factors in elderly patients with essential hypertension [J]. Practical Geriatrics, 2023,37 (02): 147-150.
[14]Yixin Yan. Risk factors for debilitating association in elderly hospitalized hypertensive patients and their impact on clinical outcomes [J]. Knowledge of cardiovascular Ds, 2023,13 (25): 9-11.
[15]Xiuping Xu, Zhu Zenghua, Zhang Mingxia. Analysis of risk factors for hypertension associated with frailty in elderly women [J]. Chinese Rural Medicine, 2021,28(06):3-4.DOI:10.19542/j.cnki.1006-5180.004998.
[16]Dan Xiao. Analysis of influencing factors of frailty in elderly hypertensive patients and construction of nomogram prediction model [J]. Clinical and Education in General Practice, 2022,20(07):617-620+673.DOI:10.13558/j.cnki.issn1672-3686.2022.007.012.
[17]Xiao-jie wang, Tiger Green Plum, Zhang Yan, et al. Analysis of the factors associated with the development of frailty in elderly hypertensive patients [J]. Ningxia Journal of Medicine, 2021,43(12):1117-1119.DOI:10.13621/j.1001-5949.2021.12.1117.
[18]Sijie Qiu, Song Jing, Fu Meiting. Study on the distribution and characteristics of hypertension in the elderly [J]. Shenzhen Journal of Integrated Traditional Chinese and Western Medicine, 2023,33(14):1-5.DOI:10.16458/j.cnki.1007-0893.2023.14.001.
[19]Jin-fang Li, Ma ley, Yu Yushan, et al. Analysis of the influencing factors of frailty in hospitalized elderly hypertensive patients in Shihezi City [J]. Guangdong Medicine, 2018,39(22):3339-3343.DOI:10.13820/j.cnki.gdyx. 20181206.009.
[20]Li Fan, Li Jianhua, Hu Yixin, et al. Frailty detection rate in elderly hypertensive patients with different complications [J]. Chinese Journal of Hypertension, 2015,23(12):1151-1155.DOI:10.16439/j.cnki.1673-7245.2015.12.018.
[21]Ling Du, Sun Ying. Risk factors for developing frailty and the impact on clinical outcomes in elderly hospitalized hypertensive patients [J]. Chinese Cardiovascular Journal, 2022,27 (02): 117-122.
[22]Yan Cheng, Li Yongle, Wang Yeon, et al. Influactors of frailty in elderly hypertensive inpatients [J]. Guangxi Medical, 2018,40 (19): 2265-2267 + 2281.
[23]Li-li Chen, Wen Liwei. Risk factors for frailty and their relationship with poor prognosis in elderly hypertensive patients [J]. Journal of Bengbu Medical College, 2020,45(10):1403-1406.DOI:10.13898/j.cnki.issn. 1000-2200.2020.10.023.
[24]Zhu, Yingqian et al. “Association between ambulatory blood pressure variability and frailty among older hypertensive patients.” Journal of clinical hypertension (Greenwich, Conn.) vol. 22,9 (2020): 1703-1712. doi:10.1111/jch.13986
[25]Sakyi, Samuel A et al. “Frailty syndrome and associated factors among patients with hypertension: A cross-sectional study in Kumasi, Ghana.” Health science reports vol. 6,10 e1664. 25 Oct. 2023, doi:10.1002/hsr2.1664
[26]B He, Ma Y, Wang C, et al. Prevalence and Risk Factors for Frailty among Community-Dwelling Older People in China: A Systematic Review and Meta-Analysis[J]. Nutr Health Aging, 2019, 23(5): 442-450.
[27]Wu Bing, Hu Yixin, Yan Jin, et al. Effect of baseline BP levels on the occurrence of long-term frailty in elderly hypertensive patients in the community [J]. Chinese Journal of Multi-organ Diseases of the Elderly, 2023,22 (06): 401-406.
[28]Coelho Junior, Hélio José et al. “Hypertension and functional capacities in community-dwelling older women: a cross-sectional study.” Blood pressure vol. 26,3 (2017): 156-165. doi:10.1080/08037051.2016.1270163
[29]Dent E,Martin Fc,Bergman H,et al. Management of frailty:opportunities,challenges,and future directions[J].Lancet,2019,394(10206):1376-86.
[30]Xi Xing, Guo Guifang. Study on the current status of the community elderly and its influencing factors [J]. Nursing Management in China, 2014,14 (12): 1315-1319.
[31]Dent, E et al. “Use of the Mini Nutritional Assessment to detect frailty in hospitalised older people.” The journal of nutrition, health & aging vol. 16,9 (2012): 764-7. doi:10.1007/s12603-012-0405-5
[32]Li Yongle. Study on the relationship between body mass index, lipid metabolism level and frailty in elderly inpatients with hypertension [D]. North China University of Science and Technology, 2019.
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