A Tricholoma Matsutake Mushroom-derived Freeze-dried Powder: Clinical Trials and Efficacy Evaluation in Skin Whitening, Brightening, Anti Photoaging, Anti-inflammatory, Anti Glycation, and Anti-aging Effects
Journal: Advanced Journal of Nursing DOI: 10.32629/ajn.v5i3.2825
Abstract
This study evaluated the efficacy of tricholoma matsutake mushroom freeze-dried powder in skin whitening, brightening, anti photoaging, anti-inflammatory, anti glycation, and anti-aging through a randomized, double-blind, placebo-controlled clinical trial. Sixty healthy female participants aged between 20 and 45 were enrolled in the study and orally administered 150mg of tricholoma matsutake mushroom-derived freeze-dried powder daily for eight weeks. Key skin parameters such as melanin index (MI), skin brightness (L* value), and individual typological angle (ITA°) were measured to assess the whitening effect, while antioxidant activity was evaluated by analyzing reactive oxygen species (ROS) reduction and DPPH free radical scavenging rates. Additionally, skin elasticity, wrinkle depth, and hydration levels were measured to evaluate anti-aging and anti-photoaging effects. Results showed a significant reduction in MI and a notable increase in both L* values and ITA° in the treatment group, indicating enhanced skin whitening. The pine mushroom extract also demonstrated potent antioxidant activity, with a 25% reduction in ROS levels and a 96% DPPH free radical scavenging rate. Anti-aging benefits were confirmed by an 18% increase in skin elasticity, a 22% decrease in wrinkle depth, and a 15% improvement in skin hydration. Furthermore, the extract provided protection against UV-induced photoaging, reducing erythema and skin texture degradation.
Keywords
tricholoma matsutake mushroom, skin whitening, anti-aging, antioxidant, clinical trial
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Copyright © 2024 Nurfarih Hanna, Mohd Zarif Fikri Bin Mohd, Muhammad Nabil Fikri Bin Mohd, Nurfarazuna Binti Mohd Fadrol
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