研究来氟米特联合厄贝沙坦治疗狼疮性肾炎的价值
Journal: Frontier Forum of Clinical Medicine DOI: 10.12238/ffcr.v3i6.17243
Abstract
目的：探究狼疮性肾炎联用来氟米特和厄贝沙坦的作用。方法：随机均分2024年1月-2025年2月本院接诊狼疮性肾炎病人（N=64）。试验组用来氟米特和厄贝沙坦，对照组用环磷酰胺和厄贝沙坦。对比尿β2-MG等指标。结果：关于尿β2-MG与24h尿蛋白定量：治疗后：试验组（1.26±0.37）mg/L、（0.63±0.39）g/d，对照组（1.97±0.48）mg/L、（1.85±0.94）g/d，差异显著（P＜0.05）。总有效率：试验组96.88%，对照组78.12%，P＜0.05。sf-36各维度评分：试验组治疗后的数据均高于对照组（P＜0.05）。不良反应：试验组6.25%，对照组25.0%，P＜0.05。结论：狼疮性肾炎病人联用来氟米特和厄贝沙坦，其用药效果和安全性均更高，且尿β2-MG等实验室指标与生活质量也都得到显著改善。
Keywords
狼疮性肾炎；来氟米特；生活质量；厄贝沙坦
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