结核病免疫反应的分子标志物
Journal: Frontiers of Chinese Medicine Research DOI: 10.12238/fcmr.v6i4.11014
Abstract
结核病(Tuberculosis,TB)仍是主要的公共卫生问题,也是导致死亡的重要原因之一。潜伏性结核感染(Latent Tuberculosis Infection,LTBI)患者发展为活动性结核病的风险增加,结核病在各阶段的诊断和早期识别问题尚未解决。现有测试(结核菌素皮肤测试和干扰素γ释放测定)虽能区分活动性和潜伏感染,但无法预测LTBI患者是否会发展为活动性结核病。本综述分析结核分枝杆菌与免疫细胞相互作用的数据,并确定其分子预测标记和早期标记。
Keywords
结核病；潜伏性结核感染；免疫细胞；细胞因子；基质金属蛋白酶
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[1] Singh S, Tanwar P, Kumar S, et al. Primary tuberculosis of the tongue in an immunocompetent patient: A case report [J].Asia Pacific Journal of Human Resources,2012,2(1):78-9.
[2] Ruhwald M, Bodmer T, Maier C. Evaluating the potential of IP-10 and MCP-2 asa biomarkers for the diagnosis of tuberculosis[J].European Respiratory Journal,2008,2008.
[3] 罗建业,邓菲丹.血清IL-12、IL-10及IL-18与肺结核的相关性研究[J].现代诊断与治疗,2015(7):1443-1445.
[2] Ruhwald M, Bodmer T, Maier C. Evaluating the potential of IP-10 and MCP-2 asa biomarkers for the diagnosis of tuberculosis[J].European Respiratory Journal,2008,2008.
[3] 罗建业,邓菲丹.血清IL-12、IL-10及IL-18与肺结核的相关性研究[J].现代诊断与治疗,2015(7):1443-1445.
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