同型半胱氨酸在孕期的临床意义及研究前景
Journal: Basic Medical Theory Research DOI: 10.12238/bmtr.v7i6.17047
Abstract
同型半胱氨酸（Hcy）是一种重要的含硫氨基酸，其代谢异常与妊娠期高血压疾病、胎儿生长受限（FGR）及复发性流产（RPL）等并发症密切相关。近年来，研究关注Hcy在孕期的变化及其对母婴健康的影响。尽管已有研究表明Hcy水平升高与这些并发症显著相关，但仍存在样本量不足和研究设计不严谨等局限，导致Hcy在孕期的具体作用机制尚不明确。本文综述孕期Hcy的变化及其对母婴健康的影响，探讨Hcy与妊娠期高血压疾病、FGR及RPL之间的关联机制，并分析当前研究的不足与未来方向，旨在为孕期Hcy的监测和干预提供理论依据，以改善母婴健康。
Keywords
同型半胱氨酸；妊娠并发症；叶酸代谢；母婴健康；发病机制
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