脑出血患者重启抗血栓治疗的研究进展
Journal: Basic Medical Theory Research DOI: 10.12238/bmtr.v7i6.17038
Abstract
脑出血为常见的卒中类型，在脑血管疾病领域占据着重要地位，其致死率与致残率均处于较高水平，给患者及其家庭带来了沉重的负担。幸存的脑出血患者，往往面临着缺血性事件的高风险。这使得抗栓药物的应用陷入两难的困境：若停用抗栓药物，患者发生缺血事件的概率会显著升高；然而，持续使用抗栓药物，又可能会增加脑出血复发的风险。尽管目前已有相关研究，以及指南支持脑出血后重启抗栓治疗，但在临床实际应用中，重启抗栓治疗的比例却很低。本研究通过检索文献，全面总结抗栓治疗的现状以及其利弊，旨在为临床决策提供有价值的参考。
Keywords
脑出血；重启；抗血栓治疗
Full Text
PDF - Viewed/Downloaded: 0 TimesReferences
[1] Schrag M, H Kirshner. Management of Intracerebral Hemorrhage: Jacc Focus Seminar [J]. J Am Coll Cardiol, 2020, 75(15):1819-1831.
[2] Korompoki E, FT Filippidis, PB Nielsen, et al. Long-Term Antithrombotic Treatment in Intracranial Hemorrhage Survivors with Atrial Fibrillation [J]. Neurology, 2017, 89(7):687-696.
[3] Collaboration R. Effects of Antiplatelet Therapy after Stroke Due to Intracerebral Haemorrhage (Restart): A Randomised, Open-Label Trial [J]. Lancet, 2019, 393(10191):2613-2623.
[4] Greenberg SM, WC Ziai, C Cordonnier, et al. 2022 Guideline for the Management of Patients with Spontaneous Intracerebral Hemorrhage: A Guideline from the American Heart Association/American Stroke Association [J]. Stroke, 2022, 53(7):e282-e361.
[5] Pasquini M, A Charidimou, CJ van Asch, et al. Variation in Restarting Antithrombotic Drugs at Hospital Discharge after Intracerebral Hemorrhage [J].Stroke,2014, 45(9):2643-2648.
[6] 张如梦,王轶群,陈甲,等.脑出血抗栓药物应用研究进展[J].中国临床神经外科杂志,2017,22:860-863.
[7] 吴炯星,王德任.脑出血后重启抗凝治疗的研究进展[J].中国卒中杂志,2020,15:45-50.
[8] Shu L, A Havenon, AL Liberman, et al. Trends in Venous Thromboembolism Readmission Rates after Ischemic Stroke and Intracerebral Hemorrhage [J]. J Stroke, 2023, 25(1):151-159.
[9] Murthy SB, C Zhang, I Diaz, et al. Association between Intracerebral Hemorrhage and Subsequent Arterial Ischemic Events in Participants from 4 Population-Based Cohort Studies [J]. JAMA Neurol, 2021, 78(7):809-816.
[2] Korompoki E, FT Filippidis, PB Nielsen, et al. Long-Term Antithrombotic Treatment in Intracranial Hemorrhage Survivors with Atrial Fibrillation [J]. Neurology, 2017, 89(7):687-696.
[3] Collaboration R. Effects of Antiplatelet Therapy after Stroke Due to Intracerebral Haemorrhage (Restart): A Randomised, Open-Label Trial [J]. Lancet, 2019, 393(10191):2613-2623.
[4] Greenberg SM, WC Ziai, C Cordonnier, et al. 2022 Guideline for the Management of Patients with Spontaneous Intracerebral Hemorrhage: A Guideline from the American Heart Association/American Stroke Association [J]. Stroke, 2022, 53(7):e282-e361.
[5] Pasquini M, A Charidimou, CJ van Asch, et al. Variation in Restarting Antithrombotic Drugs at Hospital Discharge after Intracerebral Hemorrhage [J].Stroke,2014, 45(9):2643-2648.
[6] 张如梦,王轶群,陈甲,等.脑出血抗栓药物应用研究进展[J].中国临床神经外科杂志,2017,22:860-863.
[7] 吴炯星,王德任.脑出血后重启抗凝治疗的研究进展[J].中国卒中杂志,2020,15:45-50.
[8] Shu L, A Havenon, AL Liberman, et al. Trends in Venous Thromboembolism Readmission Rates after Ischemic Stroke and Intracerebral Hemorrhage [J]. J Stroke, 2023, 25(1):151-159.
[9] Murthy SB, C Zhang, I Diaz, et al. Association between Intracerebral Hemorrhage and Subsequent Arterial Ischemic Events in Participants from 4 Population-Based Cohort Studies [J]. JAMA Neurol, 2021, 78(7):809-816.
Copyright © 2025 程学敏, 李海洪, 张为, 梁梅, 杨乙
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License