基于循证的卵巢肿瘤术后化疗患者癌因性疲劳运动方案的构建研究
Journal: Basic Medical Theory Research DOI: 10.12238/bmtr.v7i6.17029
Abstract
目的：构建基于循证护理的卵巢肿瘤术后化疗患者癌因性疲劳（CRF）运动干预方案，并验证其临床有效性。方法：基于PICOs原则系统检索国内外文献，整合高质量证据，设计包含有氧运动、抗阻训练及柔韧性训练的个性化运动方案，并制定强度、频率及动态调整策略。选取2024年1-12月重庆市某三甲医院68例卵巢肿瘤术后化疗患者（ECOG评分0-2），随机分为对照组（常规护理，n=34）和干预组（循证运动方案，n=34），干预8周。采用Piper疲乏修订量表（PFS-R）、生活质量量表（EORTC QLQ-C30）评估效果，并监测生理指标及安全性事件。结果：干预组的PFS-R评分在干预8周后由干预前（7.23±0.58）分降至（3.86±.093 ）分，显著低于同期对照组（7.63±0.43）分（P<0.001）；EORTC QLQ-30评分（ 61.16±4.04）在干预后也高于对照组（47.88±4.85 ）（P<0.001）；患者干预期间运动耐受性良好，无严重不良事件发生。结论：基于循证的运动方案可有效缓解卵巢肿瘤患者术后化疗CRF，提高患者生存质量。
Keywords
卵巢肿瘤；术后化疗；癌因性疲劳；循证护理；运动方案构建
Full Text
PDF - Viewed/Downloaded: 0 TimesReferences
[1] 李璡,温灏,刘淑娟,等.2023年中国卵巢肿瘤诊疗现状白皮书[J].中国实用妇科与产科杂志,2023,39(12):1225-1232.
[2] 中华人民共和国国家卫生健康委员会.卵巢肿瘤诊疗指南[EB/0L].(2022-04-11)[2024-12-4].http://www.nhc. gov. cn/yzygj/s2911/202204/a0e67177 df439 898 683 e1333957c74shtml.
[3] Interpretation of NCCN Clinical Practice Guidelines in Oncology：Cancer-Related Fatigue[J]. 国际转化医学杂志（英文版）,2016,4(1):1-8.
[4] Phillips S M , Mcauley E .Physical activity and fatigue in breast cancer survivors: a panel model examining the role of self-efficacy and depression.[J].Cancer Epidemiology Biomarkers and Prevention, 2013, 22(5):773-781.
[5] 李栋霜,蒋运兰,楚鑫,等.中国癌症患者癌因性疲乏影响因素的meta分析[J].现代临床医学,2021,47(2):116-119.
[6] Wagner AD, Oertelt-Prigione S, Adjei A, et al.Gender medicine and oncology: report and consensus of an ESMO workshop[J].Annals of oncology: official journal of the European Society for Medical Oncology, 2019, 30(12).
[7] 蔡红红,孙桦婷,周金华,等.卵巢肿瘤癌因性疲乏与卵巢功能丧失相关性研究[J].中国实用妇科与产科杂志,2022,38(9):925-928.
[8] 涂静.需要层次护理对晚期卵巢肿瘤化疗患者癌因性疲乏及生存质量的影响[J].基层医学论坛,2022,26(26):94-96.
[9] Susan C Modesitt 1 ,Natalie Eichner 2 ,J Kim Penberthy 3 ,Bethany J Horton 4 ,Martha E Stewart 1 ,Rachel Lacy 1 ,Arthur L Weltman 2 5 ."Moving Away From Cancer" Prospective Exercise Trial for Female Rural Cancer Survivors: How Can We Step It Up?[J].JCO oncology practice.2021,Vol.17(No.1)：e16-e25.
[2] 中华人民共和国国家卫生健康委员会.卵巢肿瘤诊疗指南[EB/0L].(2022-04-11)[2024-12-4].http://www.nhc. gov. cn/yzygj/s2911/202204/a0e67177 df439 898 683 e1333957c74shtml.
[3] Interpretation of NCCN Clinical Practice Guidelines in Oncology：Cancer-Related Fatigue[J]. 国际转化医学杂志（英文版）,2016,4(1):1-8.
[4] Phillips S M , Mcauley E .Physical activity and fatigue in breast cancer survivors: a panel model examining the role of self-efficacy and depression.[J].Cancer Epidemiology Biomarkers and Prevention, 2013, 22(5):773-781.
[5] 李栋霜,蒋运兰,楚鑫,等.中国癌症患者癌因性疲乏影响因素的meta分析[J].现代临床医学,2021,47(2):116-119.
[6] Wagner AD, Oertelt-Prigione S, Adjei A, et al.Gender medicine and oncology: report and consensus of an ESMO workshop[J].Annals of oncology: official journal of the European Society for Medical Oncology, 2019, 30(12).
[7] 蔡红红,孙桦婷,周金华,等.卵巢肿瘤癌因性疲乏与卵巢功能丧失相关性研究[J].中国实用妇科与产科杂志,2022,38(9):925-928.
[8] 涂静.需要层次护理对晚期卵巢肿瘤化疗患者癌因性疲乏及生存质量的影响[J].基层医学论坛,2022,26(26):94-96.
[9] Susan C Modesitt 1 ,Natalie Eichner 2 ,J Kim Penberthy 3 ,Bethany J Horton 4 ,Martha E Stewart 1 ,Rachel Lacy 1 ,Arthur L Weltman 2 5 ."Moving Away From Cancer" Prospective Exercise Trial for Female Rural Cancer Survivors: How Can We Step It Up?[J].JCO oncology practice.2021,Vol.17(No.1)：e16-e25.
Copyright © 2025 胡永平, 张姣姣, 杨丰, 黄萌
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License