吲哚布芬片与铝镁匹林片在心肌梗死治疗中的疗效观察
Journal: Basic Medical Theory Research DOI: 10.12238/bmtr.v7i1.11826
Abstract
目的：比较吲哚布芬片与铝镁匹林片在治疗拜阿司匹林无法耐受且合并有胃肠道反应的心肌梗死患者中的临床疗效差异。方法：选取2022年1月1日至2023年1月1日在诸暨市人民医院心血管内科住院治疗的100例无法耐受拜阿司匹林药物的心肌梗死患者,将其随机分为两组：铝镁匹林组和吲哚布芬组,每组各50例。铝镁匹林组给予常规冠心病药物联合铝镁匹林片治疗,吲哚布芬组给予常规冠心病药物联合吲哚布芬片治疗。对两组患者进行为期6个月的随访,比较两组患者在基线资料、肝肾功能、胃肠道症状、主要心血管不良事件等方面的差异。结果：两组患者基线资料无统计学差异。药物治疗6个月后,吲哚布芬组患者尿酸、肌酐水平较铝镁匹林组显著降低。吲哚布芬组患者胃肠道症状较铝镁匹林组显著降低。吲哚布芬组患者主要心血管不良事件发生率较铝镁匹林组显著降低。结论：吲哚布芬片在拜阿司匹林无法耐受的心肌梗死患者临床治疗过程中具有保护肾脏、减少胃肠道反应、改善预后等作用。
Keywords
吲哚布芬片；铝镁匹林片；心肌梗死
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