生物信息学方法研究脂肪分化过程中的差异基因
Journal: Basic Medical Theory Research DOI: 10.12238/bmtr.v7i1.11799
Abstract
目的：应用生物信息学方法鉴定脂肪分化过程中差异表达的基因。方法：利用NCBI中的GEO基因芯片公共数据库进行芯片数据搜索,最终选择数据集(GSE185481),使用软件R Studio的程序包识别差异基因。结果：通过对GSE185481进行分析,通过String和Cytoscape分析鉴定出7个枢纽基因。结论：脂肪分化过程中有差异基因的表达,本实验通过分析芯片数据(GSE185481)筛选出Hub基因：Mki67、Ccna2、Aurka、TOP2A、Cdc20、MMP9和Melk。
Keywords
生物信息学；肥胖；差异基因
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