不同周龄大鼠软骨细胞活性对比
Journal: Basic Medical Theory Research DOI: 10.12238/bmtr.v7i1.11793
Abstract
背景：关节疾病的发生与软骨细胞的活性变化密切相关。目的：本研究旨在探寻不同周龄SD大鼠的细胞活力的差异。方法：通过胰蛋白酶-II型胶原酶序贯法提取软骨细胞,细胞划痕实验观测2、4、8周龄大鼠软骨细胞的迁移能力改变。结果：对比来自较大周龄大鼠的软骨细胞,小周龄者具有更好的生长速率以及迁移能力。结论：2周龄的软骨细胞具有更好的细胞活性,迁移能力,能更便捷有效地为骨关节疾病基础研究提供更稳定的原代种子细胞。
Keywords
软骨细胞；活力；不同周龄
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