280例肺外结核临床病理特征及其耐药情况分析
Journal: Basic Medical Theory Research DOI: 10.12238/bmtr.v6i6.10989
Abstract
目的:本研究回顾性分析了280例肺外结核患者的临床病理特征及耐药情况,探讨肺外结核的诊断和治疗。方法:回顾性分析280例肺外结核病人的临床病历资料,采用MassARRAY核酸飞行质谱检测平台,分析5种一线和12种二线结核用药的耐药基因突变情况。结果:淋巴结结核最常见,肺外结核部位不同其常见病理改变也存在差异。肺外结核的耐药率为38.7%,其中利福平和异烟肼的耐药性较为常见,耐多药结核病占6.6%。结论:肺外结核的临床病理特征多样,通过对肺外结核的临床病理特征及其耐药情况的分析,可以提高肺外结核的诊断准确率和治疗效果。
Keywords
肺外结核;临床病理特征;耐药
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[4] LEE C H,RIMESSO G,REYNOLDS D M,et al. Whole-Genome Sequencing and iPLEX MassARRAY Genotyping Map an EMSinduced mutation affecting cell competition in Drosophila melanogaster[J].G3(Bethesda),2016,6(10):3207-3217.
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[6] 柴梅,史清明.肺癌合并结核病177例临床特点及影响因素分析[J].安徽医药,2021,25(5):923-926.
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[10] 余艳芳,赵开顺,屠春林,等.核酸质谱检测结核分枝杆菌耐药方法的建立[J].临床肺科杂志,2021,26(1):8.
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