术前预测肝癌微血管侵犯在检验学的研究进展

Journal: Basic Medical Theory Research DOI: 10.12238/bmtr.v6i5.10095

孙俊

青海大学附属医院

Abstract

目前,微血管侵犯(microvascular invasion,MVI)被认为是肝细胞癌(hepatocellular carcinoma,HCC)根治性切除术后与患者预后密切相关的危险因素,它不仅可以为肝癌患者的治疗方案提供重要的价值,还可以作为术后是否需要进行辅助治疗的重要指标。现阶段,一些新兴的检验学指标,如中性粒细胞、淋巴细胞、血小板、异常凝血酶原(Des-γ-carboxyl prothrombin,DCP)、甲胎蛋白(alpha fetoprotein,AFP),以及联合指标等可在术前进行预测肝癌血管的侵犯状态。以此为基础,本文将对近年来检验学预测肝癌发生微血管侵犯的方法及临床意义做一综述。旨在进一步分析检验学在临床应用中存在的难题,促进预测HCC-MVI的临床运行,此外还将对未来的研究方向进行探讨。

Keywords

肝细胞癌;微血管侵犯;检验学指标;进展

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