多项指标对结核性胸膜炎的诊断价值分析
Journal: Basic Medical Theory Research DOI: 10.12238/bmtr.v6i4.8852
Abstract
目的：探讨外周血及胸水结核感染T细胞斑点试验(T-SPOT.TB)、胸水腺苷脱氨酶(ADA)与胸水淋巴细胞优势对结核性胸膜炎的诊断价值。方法：回顾性分析2018年至2022年浙江大学医学院附属第一医院呼吸科184例胸腔积液患者的资料,其中结核性胸膜炎组102例,非结核性胸膜炎组82例；中青年组(16-59岁)100例,老年组(≥60岁)84例。结果：外周血T-SPOT.TB、胸水T-SPOT.TB、胸水T-SPOT.TB联合ADA、胸水T-SPOT.TB联合ADA及淋巴细胞优势、外周血及胸水T-SPOT.TB联合ADA、外周血及胸水T-SPOT.TB联合ADA和淋巴细胞优势在中青年组的敏感度分别为83.60%、91.80%、91.80%、98.38%、98.36%和98.38%,特异度为71.79%、89.74%、97.43%、100%、100%和100%,ROC曲线下面积为0.777、0.908、0.946、0.992、0.992和0.992；老年组的敏感度为73.17%、85.36%、90.24%、100%、97.56%和100%,特异度为74.41%、89.74%、95.34%、95.34%、95.34%和95.34%,ROC曲线下面积为0.738、0.869、0.928、0.977、0.965和0.977。结论：联合检测可提高不同年龄结核性胸膜炎的诊断效能,而且方便快捷,对于无法开展胸腔镜检查的患者,尤其是老年人群,具有重要的临床应用价值。
Keywords
结核性胸膜炎；结核感染T细胞斑点试验；腺苷脱氨酶；淋巴细胞优势
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