肠道微生态与甲状腺癌发生关系的研究进展
Journal: Basic Medical Theory Research DOI: 10.12238/bmtr.v4i4.5427
Abstract
肠道微生态由肠道微生物群、肠道粘膜和肠道免疫系统组成。近年来随着第二代高通量测序技术的兴起,肠道微生态的作用越来越多的被人们所发现。研究表明肠道微生态在人体多项生理功能的发挥中占有一席之地,当肠道微生态紊乱时会引起机体病变、甚至导致肿瘤的发生。甲状腺癌(Thyroid Cancer,TC)的发病率近几年日益增高,然发病机制目前仍不清楚,研究表明可能与肠道微生态有关。本文介绍了TC患者肠道微生态的变化以及肠道微生态紊乱导致TC发生发展的可能作用机制,在此基础上对益生菌应用于TC的治疗前景进行展望,拟为TC发病机制的探索及防治提供新思路。
Keywords
甲状腺癌；肠道微生态；肠-甲状腺轴；益生菌
Funding
内蒙古自治区卫生健康科技计划项目(202202020)。
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