子宫体中肾样腺癌一例并文献复习
Journal: Basic Medical Theory Research DOI: 10.12238/bmtr.v4i1.4794
Abstract
中肾样腺癌(mesonephric-like adenocarcinoma, MLA)是一类罕见的妇科恶性肿瘤,它被认为是一种沿中肾管分化的苗勒腺癌。该肿瘤发病率极低,子宫体发生极少。子宫体中肾样腺癌(mesonephric adenocarcinoma of the uterine corpus,UCMA)无典型的临床症状,最常表现为阴道出血,故其常需多方面结合明确诊断,如细胞学、免疫组化及分子学特征等,当中GATA3为中肾管腺癌的特异性标记物。UCMA预后不良,治疗方法常为手术和辅助性放化疗。本文根据有关文献,报道一例诊刮病理提示为UCMA患者,以期进一步提高人们对该病的认识。
Keywords
子宫肿瘤；腺癌；病例报告
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[16] Na Kiyong and Kim Hyun-Soo. Clinicopathologic and Molecular Charac teristics of Mesonephric Adenocarcinoma Arising From the Uterine Body.[J].The American journal of surgical pathology, 2019,43(1):12-25.
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[3] McFarland M,Quick CM,McCluggage WG.Hormone receptor-negative,thyroid transcription factor 1-positive uteri ne and ovarian adenocarcinomas: report of a series of mesoneph- ric-like aden ocarcinomas. Histopathology 2016;68: 1013-20.
[4] Chapel DB, Joseph NM, Krausz T, et al. An ovarian adenocarci- noma with combined low-grade serous and meson ephric morphol- ogies suggests a Müll erian origin for some mesonephric car cinomas. Am J Gynecol Pathol 2017. [Ep ub ahead of print].
[5] Yamamoto Y, Akagi A, Izumi K, et al. Carcinosarcoma of the uterine body of mesonephric origin. Pathol Int 1995; 45:303-9.
[6] Ordi J, Nogales FF, Palacin A, et al. Mesonephric adenocarci- noma of the uterine corpus: CD10 expression as evidence of mesonephric differentiati on.Am J Surg Pathol 2001;25:1540-5.
[7] Marquette A, Moerman P, Vergo te I,et al. Second case of uterine meso nephric adenocarcinoma.Int J Gynecol Cancer 2006;16:1450-4.
[8] AndoH,WatanabeY,Ogawa M, et al. Mesonephric adenocarcinoma of the ute rine corpus with intracystic growth co mpletely confined to the myometrium: a case report and literature review. Diagn Pathol 2017;12:63-70.
[9] Na K,Kim HS.Clinicopathologic and molecular character- istics of me sonephric adenocarcinoma arising from the uterine body. Am J Surg Pathol 2017. [Epub ahead of print].
[10] Patel V,KippB,Schoolmeester JK. Corded and hyalinized mesonephriclike adenocarcinoma of the uterine cor pus:report of a case mimicking endom etrioid carcinoma [J].Hum Pathol,2019, 86:243-248.
[11] Howitt BE,Emori MM,Drapkin R,et al. GATA3 Is a Sensitive andSpecif ic Marker of Benign and Malignant Mesonephric Lesions in the Lower Fem ale Genital Tract [J].Am J Surg Pathol, 2015,39(10):1411-1419.
[12] Zhang L,Cai Z,Ambelil M,et al. Mesonephric Adenocarcinoma of the Ute rine Corpus:Report of2Cases and Review of the Literature[J].IntJGynecol Path ol,2019,38(3):224-229.
[13] Kolin DL,Costigan DC,Dong F,et al.A Combined Morphologic and Molecu lar Approach to Retrospectively Ident ify KRAS -Mutated Mesonephric -like Adenocarcinomas of the Endometrium [J].Am J Surg Pathol,2019,43(3):398.
[14] Pors J,Cheng A,Leo JM,et al.A Comparison of GATA3, TTF1, CD10,and Calretinin in Identifying Mesonephric and Mesonephric-like Carcinomas of the Gynecologic Tract [J]. Am J Surg Pathol,2018,42(12):1596-1606.
[15] Mirkovic Jelena et al. Target ed Genomic Profiling Reveals Recurrent KRAS Mutations in Mesonephric-like Adenocarcinomas of the Female Genital Tract.[J].The American journal of surg ical pathology, 2018,42(2):227-233.
[16] Na Kiyong and Kim Hyun-Soo. Clinicopathologic and Molecular Charac teristics of Mesonephric Adenocarcinoma Arising From the Uterine Body.[J].The American journal of surgical pathology, 2019,43(1):12-25.
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