Rare and Dangerous Complication of Rhabdomyolysis in Critically Ill Patients: a Case Study
Journal: Journal of Clinical Medicine Research DOI: 10.32629/jcmr.v5i1.1780
Abstract
Rhabdomyolysis in critically ill patients is rare and can easily lead to serious adverse complications. We present the case of a young male patient who experienced acute liver failure resulting from closed abdominal injury, accompanied by severe complications of rhabdomyolysis and compartment syndrome. The patient underwent orthotopic liver transplantation surgery to restore liver function. Compartment syndrome of the lower legs was treated with percutaneous deep fasciotomy. Upon discharge, the patient was in a post-liver transplant state and exhibited partial dysfunction in lower limbs. Therefore, rhabdomyolysis occurs insidiously in severe patients and can easily lead to serious adverse outcomes. Clinicians should recognize symptoms of rhabdomyolysis and intervene promptly.
Keywords
acute liver failure, rhabdomyolysis, compartment syndrome
Funding
Natural Science Foundation of Tianjin Municipality (No. 20JCYBJC00990)
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[3]Stahl K, Rastelli E, Schoser B. A systematic review on the definition of rhabdomyolysis. J Neurol. 2020;267(4):877-82.
[4]Gupta A, Thorson P, Penmatsa KR, Gupta P. Rhabdomyolysis: Revisited. Ulster Med J. 2021;90(2):61-9.
[5]Wen Z, Liang Y, Hao Y, Delavan B, Huang R, Mikailov M, et al. Drug-Induced Rhabdomyolysis Atlas (DIRA) for idiosyncratic adverse drug reaction management. Drug Discov Today. 2019;24(1):9-15.
[6]Zhou T, Prather ER, Garrison DE, Zuo L. Interplay between ROS and Antioxidants during Ischemia-Reperfusion Injuries in Cardiac and Skeletal Muscle. Int J Mol Sci. 2018;19(2).
[7]Rodriguez, J, Suneja, N, von Keudell, A, & Zhang, D. Surgical demographics of acute thigh compartment syndrome. Injury. 2022;53(10), 3481-3485.
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