Research Progress on Elderly Coronary Heart Disease with Frailty

Journal: Journal of Clinical Medicine Research DOI: 10.32629/jcmr.v5i1.1770

Junpei Hu1, Jianhui Teng2, Lihui Liang3

1. Department of Geriatrics, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha 410000, Hunan, China
2. Department of Geriatrics, Hunan Provincial People's Hospital, Changsha 410000, Hunan, China
3. Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha 410000, Hunan, China

Abstract

Coronary heart disease and frailty are age-related diseases that mainly occur in middle-aged and older people. The prevalence of frailty in elderly patients with coronary heart disease is about 21%-35%. The harm of senile coronary heart disease combined with frailty is mainly manifested in the increase of sensitiveness and vulnerability, coexistence of multiple diseases, hospitalization rate, mortality, and adverse outcomes. It is essential to explore the underlying mechanisms, identify the risk factors, and evaluate the degree of frailty in a multidimensional way for personalized treatment strategies, preventing or reversing the progression of frailty and improving patients' quality of life. This article mainly studies the related research progress of stable coronary heart disease with frailty.

Keywords

the elderly, coronary heart disease, frailty

References

[1] Connie W Tsao, Aaron W Aday, Zaid I Almarzooq, Cheryl A M Anderson, Pankaj Arora, Christy L Avery, et al. Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association. Circulation. 2023; 147(8): e93-e621.
[2] S Michael Gharacholou, Joshua P Slusser, Ryan J Lennon, Carolyn R Flock, Leslie T Cooper, Patricia A Pellikka, et al. Factors associated with change in frailty scores and long-term outcomes in older adults with coronary artery disease. Journal of geriatric cardiology : JGC. 2021; 18(3): 196-203.
[3] Shin J Liau, Samanta Lalic, Janet K Sluggett, Matteo Cesari, Graziano Onder, Davide L Vetrano, et al. Medication Management in Frail Older People: Consensus Principles for Clinical Practice, Research, and Education. Journal of the American Medical Directors Association. 2021; 22(1): 43-9.
[4] Abdulla A Damluji, Shang-En Chung, Qian-Li Xue, Rani K Hasan, Jeremy D Walston, Daniel E Forman, et al. Physical Frailty Phenotype and the Development of Geriatric Syndromes in Older Adults with Coronary Heart Disease. The American journal of medicine. 2021; 134(5): 662-71.e1.
[5] Kenji Kanenawa, Kyohei Yamaji, Hiroaki Tashiro, Takeshi Morimoto, Takashi Hiromasa, Masaomi Hayashi, et al. Frailty and Bleeding After Percutaneous Coronary Intervention. The American journal of cardiology. 2021; 148: 22-9.
[6] Sandra Maria Barbalho, Ricardo José Tofano, Eduardo Federigui Baisi Chagas, Cláudia Rucco Penteado Detregiachi, Ricardo de Alvares Goulart, Uri Arian Princ Flato. Benchside to the bedside of frailty and cardiovascular aging: Main shared cellular and molecular mechanisms. Experimental gerontology. 2021; 148: 111302.
[7] Samiullah Arshad, Samina Khan, Adham Karim, Vedant A Gupta. The burden of malnutrition & frailty in patients with coronary artery disease: An under-recognized problem. JRSM cardiovascular disease. 2022; 11: 20480040221102741.
[8] Martijn Scherrenberg, Nastasia Marinus, Francesco Giallauria, Maarten Falter, Hareld Kemps, Matthias Wilhelm, et al. The need for long-term personalized management of frail CVD patients by rehabilitation and telemonitoring: A framework. Trends in cardiovascular medicine. 2022.
[9] Javier Angulo, Mariam El Assar, Alejandro Álvarez-Bustos, Leocadio Rodríguez-Mañas. Physical activity and exercise: Strategies to manage frailty. Redox biology. 2020; 35: 101513.
[10] Tarini Shankar Ghosh, Simone Rampelli, Ian B Jeffery, Aurelia Santoro, Marta Neto, Miriam Capri, et al. Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across five European countries. Gut. 2020; 69(7): 1218-1228.

Copyright © 2024 Junpei Hu, Jianhui Teng, Lihui Liang

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License