Clinical Characteristics Analysis of Hospitalized Patients Infected with the Omicron Variant of the Novel Coronavirus
Journal: Journal of Clinical Medicine Research DOI: 10.32629/jcmr.v4i3.1310
Abstract
Objective: It’s to analyze the clinical characteristics of hospitalized patients infected with the Omicron variant of the novel coronavirus. Methods: This study retrospectively analyzed the clinical data of 374 Omicron-infected patients admitted to The Third People's Hospital of Wuhu City from January 1, 2022, to December 31, 2022. Clinical characteristics were analyzed. Results: The mean time to nucleic acid conversion was 10.93±3.55 days, with a median of 10 days. There was no statistically significant difference in the infection rate between females and males (P>0.05). The highest proportion of patients was in the age group of 0-44 years (P<0.05). Among patients, those without underlying diseases were more prevalent (P<0.05). The majority of patients had no symptoms or mild symptoms (P<0.05). Regarding vaccination status, most patients had completed the primary immunization or booster immunization (P<0.05). The main symptoms were fever and respiratory symptoms (P<0.05). In laboratory tests, some patients showed a decrease in lymphocyte count (31.82%), elevated C-reactive protein (21.93%), elevated alanine transaminase (18.18%), and elevated creatine kinase (12.30%). Most patients had no lesions on chest CT scans (P<0.05). Traditional Chinese medicine was the primary treatment used (P<0.05). The recovery rate was 100.00%. Conclusion: During this epidemic, the nucleic acid conversion for infected patients occurred around 10 days. Female patients had a higher infection rate, and the majority of cases were asymptomatic or mild. Most patients had completed either primary or booster immunization, indicating some resistance of the Omicron variant to vaccines. The main symptoms were fever and respiratory symptoms, and patients had significantly elevated white blood cell counts, neutrophil counts, and lymphocyte counts, indicating significant infection symptoms. Traditional Chinese medicine was the primary treatment used, and the recovery rate was 100.00%, suggesting that treatment with Traditional Chinese medicine was effective for the Omicron variant.
Keywords
novel coronavirus, omicron variant, hospitalized patients, clinical characteristics
Funding
Wuhu Science and Technology Project (2022rkx26)
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[1] Luo, R., Liu, B., Li, Z., et al. (2023). Clinical Symptoms and RNA Clearance Time of Omicron Variant Infection in Mild Patients in Different Age Groups. International Journal of Laboratory Medicine, 44(15), 1895-1901.
[2] Zhang, W., Fang, B., Sun, D., et al. (2023). Analysis of Traditional Chinese Medicine Syndrome Characteristics in 332 Cases of Local Omicron Variant Infection Patients in Shanghai. Chinese Journal of Integrative Medicine, 43(6), 664-667.
[3] China CDC. (2020). Technical Guidelines for COVID-19 Vaccine Administration (Version 1) [EB/OL]. Available from https://www.chinacdc.cn/jkzt/crb/zl/szkb_11803/jszl_2275/202010/t20201009_218123.html
[4] Zhou, X., Yan, J., Zhao, C., et al. (2023). Clinical Characteristics Analysis of 385 Hospitalized Patients with Positive Nucleic Acid Detection for Omicron Variant of Novel Coronavirus. Clinical Pulmonary Medicine, 28(5), 668-670+676.
[5] Zhang, J., Min, Y., Zhang, J., et al. (2023). Characteristics of 88 Cases of Positive Nucleic Acid Re-Testing After Discharge in 637 Patients with Omicron Variant Infection in Suzhou. Clinical Pulmonary Medicine, 28(3), 340-344.
[6] Shi, C., Cheng, J., Zhang, J., et al. (2022). Clinical Characteristics Analysis of 144 Patients with Omicron Variant of Novel Coronavirus at the Beginning of 2022 in Suzhou. Journal of Anti-Infection Pharmacy, 19(11), 1581-1586.
[7] Zhang, Y., Li, X., Chen, F., et al. (2022). Clinical Characteristics Analysis of Patients Infected with Delta and Omicron Variants of Novel Coronavirus. Journal of Emerging Infectious Diseases (Electronic Edition), 7(3), 22-26.
[8] Zhang, Y., Xie, X., Yu, X., et al. (2022). Epidemiological Characteristics Analysis of Patients Infected with Omicron Variant of Novel Coronavirus in a Shelter Hospital in Shanghai. Chinese Journal of Epidemiology, 43(4), 311-315+341.
[9] Feng, L., Wang, X., Li, L., et al. (2022). Clinical Characteristics Analysis of Imported Omicron Variant of Novel Coronavirus in Tianjin. Tianjin Medical Journal, 50(10), 1083-1087.
[10] Liu, B., Wang, Z., Qi, X., et al. (2022). Characteristics Analysis of Elderly Patients Infected with Locally Acquired Omicron Variant During the Epidemic in Zhejiang Province. Chinese Journal of Public Health, 38(9), 1102-1107."
[2] Zhang, W., Fang, B., Sun, D., et al. (2023). Analysis of Traditional Chinese Medicine Syndrome Characteristics in 332 Cases of Local Omicron Variant Infection Patients in Shanghai. Chinese Journal of Integrative Medicine, 43(6), 664-667.
[3] China CDC. (2020). Technical Guidelines for COVID-19 Vaccine Administration (Version 1) [EB/OL]. Available from https://www.chinacdc.cn/jkzt/crb/zl/szkb_11803/jszl_2275/202010/t20201009_218123.html
[4] Zhou, X., Yan, J., Zhao, C., et al. (2023). Clinical Characteristics Analysis of 385 Hospitalized Patients with Positive Nucleic Acid Detection for Omicron Variant of Novel Coronavirus. Clinical Pulmonary Medicine, 28(5), 668-670+676.
[5] Zhang, J., Min, Y., Zhang, J., et al. (2023). Characteristics of 88 Cases of Positive Nucleic Acid Re-Testing After Discharge in 637 Patients with Omicron Variant Infection in Suzhou. Clinical Pulmonary Medicine, 28(3), 340-344.
[6] Shi, C., Cheng, J., Zhang, J., et al. (2022). Clinical Characteristics Analysis of 144 Patients with Omicron Variant of Novel Coronavirus at the Beginning of 2022 in Suzhou. Journal of Anti-Infection Pharmacy, 19(11), 1581-1586.
[7] Zhang, Y., Li, X., Chen, F., et al. (2022). Clinical Characteristics Analysis of Patients Infected with Delta and Omicron Variants of Novel Coronavirus. Journal of Emerging Infectious Diseases (Electronic Edition), 7(3), 22-26.
[8] Zhang, Y., Xie, X., Yu, X., et al. (2022). Epidemiological Characteristics Analysis of Patients Infected with Omicron Variant of Novel Coronavirus in a Shelter Hospital in Shanghai. Chinese Journal of Epidemiology, 43(4), 311-315+341.
[9] Feng, L., Wang, X., Li, L., et al. (2022). Clinical Characteristics Analysis of Imported Omicron Variant of Novel Coronavirus in Tianjin. Tianjin Medical Journal, 50(10), 1083-1087.
[10] Liu, B., Wang, Z., Qi, X., et al. (2022). Characteristics Analysis of Elderly Patients Infected with Locally Acquired Omicron Variant During the Epidemic in Zhejiang Province. Chinese Journal of Public Health, 38(9), 1102-1107."
Copyright © 2023 Chao Rui, Liyun Chen, Hui He, Fen Huang, Zhi Zhang
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