Comparison of Clinical Characteristics of First and Second Generation Cases of COVID-19

Journal: Journal of Clinical Medicine Research DOI: 10.32629/jcmr.v1i3.232

Chao Rui1, Liyun Chen1, Nengjin Gan2, Huiming Chen1, Fen Huang1, Hui He1, Zhi Zhang1

1. Department of Infectious Diseases, The Third People's Hospital of Wuhu City
2. Tuberculosis District, The Fourth People's Hospital of Ma'anshan City

Abstract

Purpose — To explore the differences in clinical characteristics of the first and second generation cases of COVID-19. Methods — 63 patients with COVID-19 and asymptomatic infections admitted to the Third People's Hospital of Wuhu City and the Fourth People's Hospital of Ma'anshan City from January 24, 2020 to March 3, 2020 were selected as the research objects. The patients were divided into the first and second generation case groups according to the history of epidemiology, and the differences of clinical data between the two groups were compared. Results — There was no significant difference between the two groups of patients in gender, age, and number of smokers (P>0.05). In the first generation group, the number of people with underlying diseases was lower than that in the second generation group (86.80%, 92.00%), and the number of patients of severe or critical type was higher than that in the second generation group (18.40%, 0.00%). The difference was statistically significant (P<0.05). The symptoms of the two groups were compared: fever (84.20%, 64.00%), cough (78.9%, 40.00%), chest tightness (44.70%, 12.00%), nausea (2.60%, 36.00%). The difference was statistically significant (P<0.05). The distribution of lesions in the two groups was compared: bilateral lung lesions (77.80%, 66.70%), unilateral lesions (17.80%, 5.50%), and no lesions (4.40%, 27.80%). The difference was statistically significant (P<0.05). There was no statistically significant difference between the two groups in laboratory tests (P>0.05). Conclusions — Compared with the first generation cases, the second generation cases have different degrees of relief in clinical classification, lower respiratory symptoms and the number of lung lesions; the differentiation of the transmission generation has a certain reference value for the evaluation of the disease condition.

Keywords

COVID-19, first generation cases, second generation cases, clinical characteristics

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Copyright © 2020 Chao Rui, Liyun Chen, Nengjin Gan, Huiming Chen, Fen Huang, Hui He, Zhi Zhang

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