脂质纳米给药系统研究进展

Journal: Basic Medical Theory Research DOI: 10.12238/bmtr.v5i5.6503

李楠

石药集团中奇制药技术(石家庄)有限公司

Abstract

近年来,脂质纳米给药系统是一种应用广泛的纳米技术,可以改善药物的生物利用度,增强靶向性,实现缓控释,并在医学影像学领域具有潜力。本文综述了脂质纳米给药系统的分类、制备技术和修饰技术等方面的研究进展。脂质纳米给药系统根据结构和组成可以分脂质纳米给药系统根据结构和组成可以分为脂质体、脂质纳米颗粒、脂肪乳以及脂质胶束等类型。制备技术包括逆向蒸发法、薄膜水化法。修饰技术可以通过改变脂质组分、添加聚合物或其他生物大分子来实现,从而改变药物的性质和释放行为。脂质纳米给药系统的发展为药物输送和治疗提供了新的途径,但仍需进一步的研究和优化。

Keywords

脂质;纳米药物;药物递送系统

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